Coupling reaction between electron-rich 2-morpholino-4(3H)-pyrimidinone and nucleophilic side chains of several natural α-amino acids promoted by phosphonium salt has been developed to prepare new optically active pyrimidin-4-yl amino acids. The best results were obtained using a two-step method through the easily available benzotriazolyl-1-oxy intermediate. A detailed optimization study of thi...

This contribution presents a real-world case study and experimentation based on the Serendipity, Ambiguity, Laterality Tangibility (SALT) conceptual architecture. We present early-stage design engineering processes (DEP) coupled with assisted human–machine creativity directed towards research Out of Lab in which we engaged public participation during nine-day international event The Netherlands...

The structure and dynamics of negatively charged nucleic acids strongly correlate with the concentration and charge of the oppositely charged counterions. It is well known that the structural collapse of DNA is favoured in the presence of additional salt, a source of excess oppositely charged ions. Under such conditions single stranded DNA adopts a collapsed coil like conformation, typically ch...

salinity stress is one of the most important abiotic stresses which threaten plants. in order to study the effect of salinity stress on yield and yield components of sunflower and also genetic analysis of these traits in relation with salt tolerance, a factorial experiment based on a completely randomized design with three replications was conducted. pots were arranged outside the greenhouse in...

background and objectives: in this study, the proteolysis and lipolysis of poosti cheese produced from raw sheep milk in mountainous eastern regions of iran were investigated during 90 days of ripening. materials and methods: sodium dodecyl sulfate polyacrylamide gel electrophoresis for proteolysis (sds-page) and gas chromatography (gc) for free fatty acids (ffas) were applied to investigate th...

1. A standard duodenal perfusion technique was used to study the effects of luminally perfused sodium taurocholate on basal and stimulated biliary and pancreatic secretion and gastrointestinal hormone release in man. 2. During duodenal perfusion with sodium taurocholate alone, both basal and caerulein/secretin-stimulated bilirubin secretion were suppressed. A successive perfusion with a mixture...

Salt stress is one of the most important factors limiting plant cultivation. Many investigations of plant response to high salinity have been performed using conventional transcriptomics and/or proteomics approaches. However, transcriptomics and proteomics techniques are not all-encompassing methods that can achieve exclusive insights into the metabolite networks contributing to biochemical rea...

Halophilic fungi have evolved unique osmoadaptive strategies, enabling them to thrive in hypersaline habitats. Here, we conduct morphological and transcriptomic response of endophytic fungus (Aspergillus montevidensis ZYD4) in both the presence and absence of salt stress. Under salt stress, the colony morphology of the A. montevidensis ZYD4 changed drastically and exhibited decreased colony pig...