CTX-M extended-spectrum β-lactamases are enzymes produced by bacteria that are capable of inhibiting the antimicrobial effects of cephalosporin drugs. Recently, the first domestically acquired Salmonella in the United States expressing bla(CTX-M) was reported. This is a concern because expanded-spectrum cephalosporins are the treatment of choice for invasive Gram-negative infections, including ...

BACKGROUND The foodborne transmission and human health impact of Salmonella and Campylobacter infections have rarely been evaluated at the population level in highly endemic settings. METHODS A prospective 15-month cohort study of 127 infants and 119 elderly people was combined with animal and food surveillance to determine the incidence and severity of Salmonella and Campylobacter gastroente...

conclusions the results indicate that multidrug-resistant (mdr) strains of salmonella are increasing in number, and fewer antibiotics may be useful for treating s. enterica infections. routine investigation and reporting of antibiotic mics in patients presenting with salmonella infections is suggested. results of the total 19 salmonella spp. isolates recovered by the bactec automated system, al...

Although Salmonella enterica is a leading cause of communityacquired bloodstream infection in Africa, these infections are frequently neglected as a target for public health intervention. The typhoidal Salmonella, serovars Typhi and Paratyphi A, cause enteric fever. Areas with high levels of endemic and epidemic typhoid fever are increasingly reported in Africa, and paratyphoid fever is describ...

bloodstream infections with salmonella typhi, is uncommon in human immunodeficiency virus (hiv)-infected persons. the symptoms in such patients are often non-specific and have a rather insidious onset and progression. we report a patient with sepsis and lower limb gangrene due to salmonella typhi infection in an hiv-infected patient.

Due to emerging resistance to traditional antimicrobial agents, such as ampicillin, trimethoprim-sulfamethoxazole, and chloramphenicol, azithromycin is increasingly used for the treatment of invasive Salmonella infections. In the present study, 696 isolates of non-Typhi Salmonella collected from humans, food animals, and retail meats in the United States were investigated for antimicrobial susc...

Salmonella is one of the major pathogenic bacteria that cause food poisoning. This study investigated whether heat-killed as well as live Lactobacillus protects host animal against Salmonella infection. Live and heat-killed Lactobacillusacidophilus was administered orally to Sprague-Dawley rats for 2 weeks before the rats were inoculated with Salmonella. Rise in body temperature was moderate in...

Young poultry exhibit a transient colonization by some food-borne pathogens, including Salmonella, during the first week of life that stems from immature innate and acquired defense mechanisms. Consequently, modulation of the hosts' natural immune response is emerging as an important area of interest for food animal producers, including the poultry industry. Toll-like receptor (TLR) agonists ha...

It was investigated how organic rearing conditions influence the Salmonella enterica infection dynamics in pigs and whether Salmonella persists in the paddock environment. Pigs inoculated with S. enterica serovar Typhimurium were grouped with Salmonella-negative tracer pigs. Bacteriological and serological testing indicated that organic pigs were susceptible to Salmonella infections, as 26 of 4...