Ductal papillomas have unique papillary features arising from the salivary gland duct system. They comprise three rare benign adenomas, namely, inverted ductal papilloma, sialadenoma papilliferum, and intraductal papilloma. Intraductal papilloma is an extremely rare benign salivary gland tumor that occurs most commonly in the minor salivary glands. Here, we are presenting a case report of intra...

The salivary glands are divided into major and minor/accessory glands. Tumours are not rare in salivary glands and are mainly found in major salivary glands. Tumours of accessory salivary glands are relatively less common. Accessory parotid gland is a small unit of salivary gland tissue lying on the masseter muscle and seperated from the main parotid gland with an accessory duct draining into t...

It has been reported that cimetidine, a histamine type-2 receptor (H2R) antagonist, inhibits the growth of glandular tumors such as colorectal cancer. However, its effects against salivary gland tumors are still unknown. We demonstrated previously that human salivary gland tumor (HSG) cells spontaneously express the neural cell adhesion molecule (NCAM) and also that HSG cell proliferation could...

PURPOSE The nitroxide free radical, Tempol, was evaluated for potential differential radiation protection of salivary glands and tumor using fractionated radiation. Mechanistic information was explored by monitoring the presence and bioreduction of Tempol in both tissues noninvasively by magnetic resonance imaging (MRI). EXPERIMENTAL DESIGN Female C3H mice were immobilized using custom-made L...

Aim: To identify the association of vascular endothelial growth factor (VEGF) immunoexpression in progression salivary gland tumor. Study design: Comparative cross-sectional study Place and duration study: Department Pathology, Peshawar Medical College. Duration was six months from date approval. Methodology: Forty five specimen tumor were studied which 30 benign 15 malignant. The endpoint asse...

mucoepidermoid carcinoma is a neoplasm of salivary gland origin, and its laryngeal occurrence is extremely rare. this malignant tumor is composed of two distinct cell types, the epidermoid and mucus cells. prognosis is largely dependent on the histologic pattern. in this report, an extremely rare laryngeal cancer and its clinicopathologic features are described.

INTRODUCTION Tumor necrosis factor is a pleiotropic cytokine with potent immune regulatory functions. Although tumor necrosis factor inhibitors have demonstrated great utility in treating other autoimmune diseases, such as rheumatoid arthritis, there are conflicting results in Sjögren's syndrome. The aim of this study was to assess the effect of a locally expressed tumor necrosis factor inhibit...

The aim of this study was to investigate the radioprotective effect of thymol as a natural product against salivary glands dysfunction induced by ionizing radiation in rats. The rats were treated with thymol at dose of 50 mg/Kg before exposure to radiation at dose 15Gy. Salivary gland function was evaluated with radioisotope scintigraphy and then salivary gland to background counts ratio was ca...

Epithelial-myoepithelial carcinoma (EMC) is considered as a rare malignant salivary gland neoplasm with good prognosis, low recurrence rate and rare metastasis. Here we present a case of epithelial-myoepithelial carcinoma in a 42-year-old female with a swelling of 3-year duration in her palate. Histopathologic evaluation of the lesion demonstrated a well-circumscribed, biphasic salivary gland t...

BACKGROUND Pleomorphic adenomas are benign salivary gland tumors, which predominantly affect the superficial lobe of the parotid gland. The "pleomorphic" nature of the tumor can be explained on the basis of its epithelial and connective tissue origin. The tumor has a female predilection between 30-50 years of age. Slowly progressing asymptomatic swelling is the usual presentation of the tumor. ...