The synthesis of covalent organic frameworks (COFs) based on a novel thiophene-extended benzotrithiophene (BTT) building block is described, which in combination with triazine-based amines (1,3,5-triazine-2,4,6-triyl)trianiline (TTA) or (1,3,5-triazine-2,4,6-triyl)tris(([1,1´-biphenyl]-4-amine)) (TTTBA)) affords crystalline, and porous imine-linked COFs, BTT TTA TTTBA, surface areas as high 932...

A new dinuclear Cd(II)-azido complex of 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (PMT) pincer ligand is synthesized. Its single crystal X-ray structure reveals the [Cd(PMT)(Cl)(N3)]2 formula. The triclinic parameters are a = 9.323(4) Å, b 10.936(5) c 11.312(6) ? 112.637(10)°, ? 104.547(11)° and ? 105.133(10)° while V 944.1(8) Å3. Due to symmetry considerations, asymmetric ...

We describe a simple, economical procedure for rapidly detecting acetaminophen in serum or plasma. The method is based upon the reduction by the drug of ferric 2,4,6-tris(2-pyridyl)-s-triazine, at an acidic pH, to ferrous 2,4,6-tris(2-pyridyl)-S-triazine complex, which absorbs maximally at 593 nm. Absorbance and acetaminophen concentration are linearly related from 25 to 400 mg/L, and so therap...

An investigation was undertaken to study the factors which cause grossly elevated values in an automated procedure for chloride when the sample is contaminated with bromide. The questioned mercuric thiocyanate method of the autoanalyzer was compared to a similar system utilizing mercuric 2, 4, 6-tripyridyl-s-triazine as a substitute ligand source in the chloride exchange system. It was determin...

T he conform ations and electronic p roperties of several u rea/am ide, uracil, s-triazine and m ethylth iopyrim idine inhibitors of photosystem II were determ ined using m olecular m echanics (C H A R M M , SY BYL) or quan tum sem i-em pirical (M N D O , A M I) m ethods. Spectroscopic m easu rem en ts o f the in vitro hydrogen bonding capacity of these com pounds w ere also carried ou t. T he ...

Convenient syntheses of mono- and bis-imidazolium 1,3,5-triazine derivatives bearing piperidine and morpholine substituents are reported. In situ deprotonation of the mono-imidazolium salts and reaction with Ag2O or Au(tht)Cl (tht = tetrahydrothiophene) precursors affords the corresponding Ag(NHC)Cl and Au(NHC)Cl carbene complexes. In the presence of Ag(I) or Au(I) salts the bis-imidazolium pin...

The s-triazine cyclopropylmelamine (N-cyclopropyl-1,3,5-triazine-2,4,6-triamine) was degraded to about 6 mol of NH4+/mol of substrate by a mixture of two bacteria (strains A and D, both Pseudomonas spp.) Only strain A grew with cyclopropylmelamine as sole and limiting source of nitrogen. The organism obtained 2 mol of nitrogen/mol of substrate and excreted a product that was identified as cyclo...

Enrichment cultures utilizing deethylsimazine (6-chloro-N-ethyl-l,3,5-triazine-2,4-diamine) as a sole nitrogen source were obtained from so5 that had had long exposure to s-triazine herbicides. A bacterium was isolated that utilized deethylsimazine quantitatively as a nitrogen source for growth, but only 1 mol of nitrogen was obtained/mol of deethylsimazine, whereas all six atoms in melamine we...

Dihydrofolate reductase (DHFR) is an important enzyme for de novo synthesis of nucleotides in Plasmodium falciparum and it is essential for cell proliferation. DHFR is a well known antimalarial target for drugs like cycloguanil and pyrimethamine which target its inhibition for their pharmacological actions. However, the clinical efficacies of these antimalarial drugs have been compromising due ...