This study aimed to determine the diagnostic utility of mast cell densities in distinguishing neurotised ("neural") melanocytic naevi from neurofibromas. Three groups of lesions were studied: neurofibromas, neural naevi, and naevi showing no neural change (control naevi). A Giemsa stain was used to demonstrate mast cells. The median mast cell density in the neurotised naevus group was significa...

Bioptic specimens from 224 melanocytic naevus lesions and 121 seborrheic keratosis lesions were stained with hematoxylin-eosin and examined under the light microscope. Pityrosporum ovale/orbiculare (Malassezia furfur) was found in 35% of melanocytic naevi and in 36% of seborrheic keratoses. The finding of Pityrosporum ovale/orbiculare was confirmed by PAS (periodic acid shift), methenamide silv...

Sir, Syringocystadenoma papilliferum (SCAP) is a rare tumour first described in 1893 (1). To date, 400 cases have been reported worldwide. SCAP usually appears at birth or in early childhood, most frequently on the face or scalp. In approximately 25% of cases it is observed on other locations such as the trunk or the extremities. In 40% of cases, SCAP evolves contiguous to a pre-existing naevus...

INTRODUCTION Combined malignant naevi are characterised pathologically by the association of a melanoma with one or more different types of benign melanocytic naevi in a single lesion. CASE PRESENTATION We show here a case of malignant combined naevus made up of a blue naevus and a melanoma, presenting as a slowly progressing and asymptomatic pigmented lesion on the trunk of a 35-year-old man...

1. Cornbleet T, Bernstein R, Kroll C. Observations on leukoderma acquistum centrifugum. Arch Dermatol. 1960;82:1011-2. 2. Meyerson KB. A peculiar papulosquamous eruption involving pigmented naevi. Arch Dermatol. 1971;103:510-2. 3. Del Río E, Aguilar A, Gallego MA. Targetoid halo nevus. J Am Acad Dermatol. 1993;29:267-8. 4. Fabrizi G, Massi G. Halo naevus with histological changes resembling epi...

Le naevus bleu cellulaire atypique est une entité pathologique rare et sa localisation au niveau du poignet est exceptionnelle. Il est Considéré comme une Variante à des caractéristiques intermédiaires entre le naevus bleu cellulaire typique et le naevus bleu malin, dont l'évolution est incertaine. Le but de notre travail est d'attirer l'attention sur cette variété lésionnelle rare et de discut...

Epidermolysis bullosa naevi are large, eruptive melanocytic naevi which frequently arise in areas of former blisters in patients suffering from inherited epidermolysis bullosa. Morphologically, these naevi are similar to malignant melanoma, although so far no malignant transformation has been observed. To investigate the pathogenesis of these moles we documented their clinical evolution and the...

Epidermal naevi are hamartomas that are characterized by hyperplasia of the epidermis and adnexal structures and may be associated with serious disfiguration. Management of epidermal naevi is challenging. We present here our experience with cryosurgery in the treatment of verrucous epidermal naevi. The aim of this study was to determine the efficacy and safety of cryosurgery for the treatment o...