Protein S-palmitoylation is a reversible post-translational modification of proteins with fatty acids. In the last 5 years, improved proteomic methods have increased the number of proteins identified as substrates for palmitoylation from tens to hundreds. Palmitoylation regulates protein membrane interactions, activity, trafficking and stability and can be constitutive or regulated by signallin...

Glutathione S-transferases (GSTs) are ubiquitous enzymes and abundant in plants. They are intimately involved in plant metabolism and stress defense related to reactive oxygen species. Our project assigned particular reactions including novel ones to certain GST-isoforms. Transformed E. coli was used to express recombinant GST-isoforms from maize. An N-terminal His tag allowed their purificatio...

A set X ⊆ N is S-recognizable for an abstract numeration system S if the set repS(X) of its representations is accepted by a finite automaton. We show that the growth function of an S-recognizable set is always either Θ((log(n))n ) where c, d ∈ N and f ≥ 1, or Θ(nrθΘ(nq)), where r, q ∈ Q with q ≤ 1. If the number of words of length n in the numeration language is bounded by a polynomial, then t...

Phosphorylation of histone H2AX by ATM and ATR establishes a chromatin recruitment platform for DNA damage response proteins. Phospho-H2AX (γH2AX) has been most intensively studied in the context of DNA double-strand breaks caused by exogenous clastogens, but recent studies suggest that DNA replication stress also triggers formation of γH2A (ortholog of γH2AX) in Schizosaccharomyces pombe. Here...

It is demonstrated, that 't Hooft's renormalization scheme (in which the β-function has exactly the two-loop form) is generally in conflict with the natural physical requirements and specifies the type of the field theory in an arbitrary manner. It violates analytic properties in the coupling constant plane and provokes misleading conclusion on accumulation of singularities near the origin. It ...

In this research, we propose a bi-objective model for the economic-statistical design of the X-bar and S control charts. The model minimizes out-of-control average time to signal as well as minimizing mean hourly loss-cost where it incorporates the Taguchi loss function. Statistical constraint is considered in the model to achieve desired in-control time to signal. A non-dominated sort...

It is shown that Ramanujan could have proved a special case of his conjecture that his tau function is multiplicative without any recourse to modularity results.

The single-particle nuclear potential is intrinsically nonlocal. In this paper, we consider nonlocalities which arise from the many-body and fermionic nature of the nucleus. We investigate the effects of nonlocality in the nuclear potential by developing the Green’s function for nonlocal potentials. The formal Green’s function integral is solved analytically in two different limits of the wavel...

Parkinson’s disease is the second most common age associated neuron degenerative disorder in developed societies. With the prevalence ranging from 41 per 100000 in the fourth decade of life to over 1900 per 100000 in people over 80 years of age.it characterized clinically by resting tremor, slowness of movement, rigidity and postural instability in the result of progressive loss of dopami...

this bipartite paper examines the function of tasrif in the quranic story of creation in the light of halliday's textual meta-function. first, the quranic concept of tasrif as a field in elm-al maani (semantics of syntax), and its relation to systemic linguistics is introduced and reviewed. then, through review of literature, it is referred to givenness hierarchy, empathy degree, point of ...