Background The clock genes controlling biological rhythm play an important role in the pathophysiology of aging. The purpose of this study was to determine whether there is an association between a variant of the circadian locomotor output cycles kaput (CLOCK) gene and circadian dysfunction of Parkinson's disease (PD). Methods Six hundred and forty-six cases of Parkinson's disease from consec...

in recent years, emotion dysregulation and anxiety sensitivity have been introduced of the most effective factors in sleep disturbance. the purpose of this study was to examine emotion dysregulation and anxiety sensitivity as potential contributor to sleep problems in students. the statistical population of this research consisted of all the bu-ali sina university’s students in the academic yea...

OBJECTIVES Caregivers of patients with various diseases frequently report sleep disturbances and depressive symptoms. Care intensity for individuals with Parkinson's disease is mainly influenced by the severity of their motor impairment. The latter is associated with sleep fragmentation, nocturnal pain and cramps. These disease-specific characteristics contribute to sleep-related problems in pa...

OBJECTIVES The aims of this study were to explore nocturnal disturbances in patients with Parkinson's disease (PD) and to assess their impact on quality of life (QoL). METHODS A total of 211 patients with PD were recruited for this study, and each participant was evaluated using the mini-mental state examination, PD sleep scale - second version (PDSS-2), pittsburgh sleep quality index (PSQI),...

the quality of life of 50 end stage renal disease (esrd) patients on hemodialysis was evaluated before and after kidney transplantation (ktx). mean duration of the patients' hemodialysis was 3 years and mean postoperative period was 2.4 years when tested. common problems of such patients such as depression, sleep disorders, energy pattern disruption, sex-life difficulties, and appetite dis...

STUDY OBJECTIVE To examine the spectrum of sleep disorders in patients with chronic traumatic brain injury (TBI) and determine if the severity of sleep disorder is related to severity of chronic TBI. METHODS Patients who underwent evaluation for sleep disorder/s following a TBI were included in this retrospective analysis. Sixty adult patients with TBI (age 20-69 yr; 38 M and 22 F), who prese...

Abundant evidence suggests that sleep might be altered during infectious disease, although the relationship between sleep and infectious disease has never been examined systematically. To address this issue, we determined the effects of Staphylococcus aureus infection on rabbit sleep. Rabbits inoculated intravenously with S. aureus demonstrated the expected physiological changes consistent with...

backgroundattention deficit/hyperactivity disorder (adhd) is one of the most common neurodevelopmental disorders of childhood. up to 50% of these children suffer from at least one comorbid sleep disorder. considering the deleterious effects of sleep problems on all aspects of children's life, this study was designed to investigate the impact of a sleep hygiene intervention on sleep habits ...

BACKGROUND Poor sleep quality is common in rheumatoid arthritis (RA) patients and may lead to disease aggravation and decreased health-related quality of life (HRQoL). The increasing prevalence of poor sleep in RA patients is associated with adverse demographic, clinical, and psychological characteristics. However, there are currently no known reported studies related to the effects of sleep qu...

BACKGROUND Although considerable progress has been made in the treatment of chronic kidney disease, compromised quality of life continues to be a significant problem for patients receiving hemodialysis (HD). However, in spite of the high prevalence of sleep complaints and disorders in this population, the relationship between these problems and quality of life remains to be well characterized. ...