BACKGROUND Kawasaki disease is the most common cause of acquired cardiac disease and acute vasculitis in children, targets the coronary arteries, and can occasionally be fatal. The pathogenesis and the molecular mechanisms remain unknown. After injection of Lactobacillus casei cell-wall extract (LCCWE), mice develop a focal coronary arteritis that histopathologically resembles Kawasaki disease,...

OBJECTIVE Nod1 is an intracellular pattern recognition receptor for bacterial peptidoglycan fragments. We previously reported that a synthetic Nod1 ligand, FK565, induced acute coronary arteritis in mice similar to that of Kawasaki disease. However, the molecular mechanisms underlying this characteristic inflammation have remained elusive. APPROACH AND RESULTS We found that CD11c(+)MHC class ...

Giant cell arteritis (GCA) is a systemic granulomatous vasculitis of unknown aetiology, which typically affects the branches of carotid artery (especially the temporal artery), but it can involve any medium-size or large artery, and then its diagnostics becomes much more difficult. The aim of our study is to point up typical histopathological changes in the aorta of GCA patients. In the study w...

background: takayasu arteritis is a granulomatous vasculitis which mainly involves the large arterial vessels. the disease is rare and it is more common in females aged between 15-30 years old. in this paper, we report a case of takayasu arteritis in babol, north of iran. case presentation: a 22 - year old female was admitted to the department of infectious diseases of rouhani teaching hospital...

INTRODUCTION Giant cell arteritis is the most common form of large-vessel vasculitides. However, it is probable that extracranial involvement is underdiagnosed in patients with classical giant cell arteritis. In the recent literature most cases of giant cell arteritis have been described in conjunction with aortic aneurysms or dissections. Nonetheless the coexistence of giant cell arteritis and...

A 44-year-old housewife was found to have coarctation of the abdominal aorta secondary to Takayasu's arteritis. Since she also had mitral stenosis, possible etiological relation between Takayasu's arteritis and mitral stenosis is suspected.

Cogan's syndrome may be associated with large-vessel arteritis. We describe a patient with ocular inflammation, sensorineural hearing loss and arm claudication in whom a diagnosis of 'atypical' Cogan's syndrome and Takayasu's arteritis was made. All symptoms resolved with treatment.

takayasu’s arteritis (ta) is a rare case of granulomatous arteritis which mainly involves the aorta and its large branches. although arterial hypertension is the most common feature of the disease in both adults and children, patients with ta may present with numerous clinical manifestations. our patient was a 45-year-old woman, known to have hypertension from 3 years earlier following assessme...

Takayasu`s arteritis is a well-known systemic disease that involves the aorta, major aortic branches, and pulmonary arteries. Conventional catheter angiography remains the gold standard for disease diagnosis, in correlation with clinical data and laboratory findings. Multislice computed tomography angiography (MSCTA) has the advantage of non-invasively providing the angiographic data and combin...

neurological manifestation may complicate takayasu arteritis (ta). a 23-year-old girl with sudden onset of vision loss was admitted to hospital. her brain mri showed abnormal t2-signal hyperintensity and visual evoked potential revealed prolonged p100 latency. consequently, optic neuritis was diagnosed. a review on history of dizziness, falling, and weak pulses of upper extremities led to more ...