Buckwheat is an important minor crop with pharmaceutical functions due to rutin enrichment in the seed. Seeds of common buckwheat cultivars (Fagopyrum esculentum, Fes) usually have much lower rutin content than tartary buckwheat (F. tartaricum, Ft). We previously found a wild species of common buckwheat (F. esculentum ssp. ancestrale, Fea), with seeds that are high in rutin, similar to Ft. In t...

A capillary electrophoresis with electrochemical detection was developed for the simultaneous determination of three flavonoids (naringenin, rutin, quercetin) and ascorbic acid. It was found that naringenin, rutin, quercetin and ascorbic acid were well separated within 5 min in borate buffer solution (pH 8.6, 24 mM). The detection limit was 1.0 microM for naringenin, 8.0 microM for rutin, 2.0 m...

background and objectives: rutin, quercetin and liquiritin arepolyphenol flavonoids which have shown anti-inflammatory, antihepatotoxic, antiulcer, antiallergic, antidiabetic, antiviral and antioxidant activities. they are found in many herbal plants, one of them is cocculus hirsutus.  the objective of this research was to develop and validate a new, accurate, precise and economic hptlc method ...

Rutin is a polyphenolic naturally occurring compound potentially having a huge impact in human benefit which includes wound healing, cardiovascular, carcinoma therapeutic activities as well as have nutraceutical benefits. The objective of study was to establish a precise, accurate, sensitive and reliable method for estimation at low concentrations of rutin in biological fluids, using spectroflu...

The flavonoids quercetin, and its natural glycosides isoquercetin and rutin, are phytochemicals commonly consumed in plant-derived foods and used as a food beverage additive. Semi-synthetic maltooligosyl isoquercetin, monoglucosyl rutin and maltooligosyl rutin were developed by synthetic glycosylation to improve their water solubility for food and other applications. Using a system of Chinese h...

Phenolic and flavonoid compounds are secondary metabolites of plants which possess various activities such as anti-inflammatory, analgesic, anti-diabetes and anticancer effects. It has been established that these compounds can scavenge free radicals produced in the body. Because of this ability, not only the plants containing phenolic and flavonoid compounds but also, the pure compounds are use...

the potential of tobacco waste as a viable source of medicinally important flavonoids like rutin has been investigated. three flavonoids, apigenin, quercetin and rutin, have been isolated from waste tobacco leaves, and their identities have been confirmed by uv-visible, 1h-nmr and 13c-nmr spectroscopy. by using analytical hplc, the amount of rutin present in the tobacco leaves, before and after...

Methods Twenty-four rats were divided into 4 groups: sham + saline, sham + rutin, 2K1C + saline and 2K1C + rutin. Six weeks after 2K1C surgery, animals presented hypertension compared to the control group (142 ± 2 mmHg versus 121 ± 2 mmHg, n = 8, p <0.05), while there was no change in heart rate. After six weeks, animals were treated with saline or rutin (30 mg/kg/day) by gavage for 14 days. Th...

The electrochemical behaviors of rutin at a poly(p-aminobenzene sulfonic acid) modified glassy carbon electrode (PABSA/GC) have been investigated. Rutin can generate a pair of well-defined redox peaks at the PABSA/GC located at 0.440 V (E(pa)) and 0.396 V (E(pc)) (vs. saturated calomel electrode (SCE)), respectively. The results indicate that the reaction involves two electrons transfer, accomp...

The present study investigated the effect of rutin on high glucose-induced actin, α2, smooth muscle, aorta (ACTA2) and p38 protein expression in diabetic nephropathy (DN). Human mesangial cells were divided into a control group, high glucose-induced mesangial cell group, high glucose + captopril group, and high glucose + rutin group (low, middle and high doses of rutin). Cell viability, adenosi...