DNA vaccines are potential tools for the induction of immune responses against both infectious disease and cancer. The dermal application of DNA vaccines is of particular interest since the epidermal and dermal layers of the skin are characterized by an abundance of antigen-presenting cells (APCs). The aim of our study was to compare tumor protection as obtained by two different methods of intr...

Cornell University, in collaboration with Jefferson Laboratory, has proposed the construction of a 100 MeV, 100 mA CW Energy Recovery Linac (ERL) prototype, to study and resolve the many accelerator physics and technology issues of this type of machine. The long term goal of this work is the construction of a state-of-the-art 5 to 7 GeV ERL-based synchrotron light source. A key element of this ...

Heat exchangers are widely used in power engineering and industrial applications, many techniques such as coiled tube, surface tension devices, rough surfaces, extended surfaces have been investigated to enhancethermal performance and to minimize the cost and size of the heat exchanger equipment. One of the most important techniques is tube insert. In general,tube inserts can be classified into...

Determining injector-producer relationships, i.e., to quantify the inter-well connectivity between injectors and producers in a reservoir, is a complex and non-stationary problem. In this paper, we present a neural-network-based sensitivity analysis approach to address this problem. To the best of our knowledge, sensitivity analysis has never been applied for identification of the injector-prod...

generally, fatigue failure in an element happens at the notch on a surface where the stress level rises because of the stress concentration effect. the present paper investigates the effect of a notch on the fatigue life of the hsla100 (­high strength low alloy) steel which is widely applicable in the marine industry. tensile test was conducted on specimens and mechanical properties were obtain...

The occurrence of vortices in the sac volume automotive multi-hole fuel injectors plays an important role development vortex cavitation, which directly influences flow structure and emerging sprays that, turn, influence engine performance emissions. In this study, RANS-based turbulence modelling approach was used to predict internal a vertical axis-symmetrical (6) diesel injector under non-cavi...

At low pressure, ethylene gas consists of single translating and rotating molecules and behaves as an ideal gas. With decrease of free volume by compression, various rotating supramolecular particles are formed, which require less space for the movement: molecular pairs, bimolecules and oligomolecules. The appearance of a new kind of particles is manifested as a phase transition of the second o...

With the development of highly-deviated well cementing techniques, rotating casing cementing technology has got more and more attention. The rotating casing technique can improve the displacement efficiency of cement paste, and then enhance the quality of well cementation. In the stuck section, the rotating casing can redress the well to make the casing run sequentially. The casing endures shea...

EUROTRANS is a European research program for the transmutation of high level nuclear waste in an accelerator-driven system (ADS). As proposed, the driver linac needs to deliver a 2.5–4 mA, 600 MeV continuous-wave (CW) proton beam and later a 20 mA, 800 MeV one to the spallation target in the prototype-scale and industrial-scale demonstration phases, respectively. This paper is focusing on the c...