نتایج جستجو برای: rihan 03
تعداد نتایج: 31145 فیلتر نتایج به سال:
We recently identified the protein phosphatase-1 - targeting compound, 1E7-03 which inhibited HIV-1 in vitro. Here, we investigated the effect of 1E7-03 on HIV-1 infection in vivo by analyzing its metabolic stability and antiviral activity of 1E7-03 and its metabolites in HIV-1 infected NSG-humanized mice. 1E7-03 was degraded in serum and formed two major degradation products, DP1 and DP3, whic...
BACKGROUND Data on allele frequencies (AFs) and haplotype frequencies (HFs) of HLA-C and -DQB1 are limited in Koreans. We investigated AFs and HFs of HLA-A, -B, -C, -DRB1, and -DQB1 in Koreans by high-resolution sequence-based typing (SBT). METHODS Hematopoietic stem cells were obtained from 613 healthy, unrelated donors to analyze HLA-A, -B, -C, -DRB1, and -DQB1 genotypes by using AlleleSEQR...
Because of the potential of a new anti-staphylococcal lead compound SK-03-92 as a topical antibiotic, a patch, or an orally active drug, we sought to determine its safety profile and oral bioavailability. SK-03-92 had a high IC50 (125 μg/ml) in vitro against several mammalian cell lines, and mice injected intraperiteonally at the highest dose did not exhibit gross toxicity (e.g. altered gait, u...
Franco Gherlinzoni, M.D., (1999–02) Michael Simon, M.D., (1999–02) Scott Nelson, M.D., (1999–02) Martine van Glabbeke, M.D., (1999–02) Ephraim Casper, M.D., (2000–03) Andrew Huvos, M.D., (2000–03) Martin Robinson, M.D., (2000–03) Junya Toguchida, M.D., (2000–03) Kristy Weber, M.D., (2001–04) Jean Yves Blay, M.D., (2001–04) Thomas DeLaney, M.D., (2001–04) Pancras Hogendoorn, M.D., (2001–04) H.J....
2. Project Title: Conditional knock-out of GnRH neurons and its effects on development, emotionality and behavior in mice 3. Japanese Investigator ’s Name, Title, Affiliation and Phone Number: Chief : Yasuo Sakuma, Professor, Nippon Medical School, Tel: 03-3824-6640 Collaborators: Kunihiko Obata, Professor, National Institute for Physiological Sciences, Tel: 0564-55-7700 Masakatsu Kato, Associa...
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