conclusions prp dressing could significantly decrease the depth and surface area of dfus in a three-week period. background some of the studies confirmed the effectiveness of platelet rich plasma (prp) in the treatment of diabetic foot ulcers (dfu). however, these studies had small sample size and used different methods such as prp gel or prp injections. the results are also contraversial. obje...

background:the aim of this study is to find out the spatial and temporal expression of tgf-b1 during the tendon healing, after application of platelet rich plasma (prp). methods: a patellar tendon defect model in rabbits was used for this purpose. 48 skeletally mature new zealand white rabbits, weighing 3.5 kg, were used for this study. equal numbers of animals from both groups were sacrificed ...

objectives:  the efficacy of adding platelet-rich plasma (prp) to demineralized freeze-dried bone allograft (dfdba) in order to improve the clinical and radiographic results obtained in treatment of deep periodontal intrabony defects has yet to be fully elucidated. materials ­and methods: this double blind, split-mouth randomized controlled clinical trial was conducted on 12 patients with two c...

PURPOSE To evaluate the influence of PRP addition on bone repair of circular defects created in irradiated tibiae of rats by histometric analysis. METHODS Sixty male Wistar rats had the right tibiae irradiated with 30 Gy. After 30 days monocortical defects were created and platelet-rich plasma was applied in 30 rats. In the control group defects were created but not filled. The animals were d...

Background: Cell therapy and cell culture have received much attention in recent decades. Suitable cell growth requires growth supplements such as fetal bovine serum (FBS). FBS is component rich in nutrients, growth factors and supplementary compounds. However, FBS utilization has some limitations including mass production. Therefore, finding alternatives with the same growth promoting effects ...

This was Presented in 5th International Congress of Iranian Iranian Society of Knee Surgery, Arthroscopy, and Sports Traumatology (ISKAST), 14-17 Feb 2018- Kish, Iran

The formation of thrombi in vivo includes the activation of both platelets and the coagulation cascade. Conventional thrombolytic therapy is primarily directed toward the dissolution of fibrin. To evaluate the possibility that platelet activity impairs the lysis of thrombi, we studied the effects of aspirin and platelet-deaggregating prostaglandin El on thrombolysis with urokinase. Combined pla...