pneumorrhachis (pr), which involves the entrapment of air or gas within the spinal canal, is a rare clinical entity. the pathogenesis and etiology of this uncommon entity vary and may present a diagnostic challenge. air in the spinal canal can be divided into primary and secondary pr, extra- or intradural pr and etiologically classified as iatrogenic, traumatic and non-traumatic. pr is typicall...

Background: The aim of this study was to evaluate and compare the clinical and ‎electrocardiographic (ECG) manifestations of benzodiazepines (BZs).‎ Methods: In this retrospective study, all BZ-poisoned patients hospitalized at Loghman ‎Hakim Hospital between September 2010 and March 2011 were evaluated. Patients’ ‎information including age, sex, time elapsed between the ingestion and presenta...

Background: Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation. However, HESCs also abundantly express androgen receptors (AR), yet the role of this member of the superfamily of ligand-dependent transcription factors in the decidual process remains poorly elucidated. Materials a...

Sequencing Experiments in Drug Discovery Diana M. Negoescu Department of Management Science and Engineering, Stanford University, Stanford, CA 94305, USA, Peter I. Frazier School of Operations Research and Information Engineering, Cornell University, Ithaca, NY 14853, USA, Warren B. Powell Department of Operations Research and Financial Engineering Princeton University, Princeton, NJ 08544, USA...

There is a bewildering array of methods for estimating animal home ranges, including minimum convex polygons, bivariate ellipses, adaptive and fixed kernels, and even a Brownian bridge technique (Bullard 1991; Kernohan et al. 2001). Many people believe that the fixed kernel method using least-squares cross validation (LSCV) is the best approach currently available (Seaman and Powell 1996; Powel...

The conjugate gradient approach is a powerful tool that used in variety of areas to solve problems involving large-scale reduction. In this paper, we propose new parameter nonlinear algorithms fuzzy equations based on Polak and Ribiere (PRP) method, where prove the descent global convergence properties proposed algorithm. terms numerical results, method has been compared with methods Fletcher (...