1. Burns DA. Necrobiotic disorders. In: Burns T, Breathnach S, Cox NH, Griffiths C, editors. Rook’s text book of dermatology. 8th ed. Oxford: Wiley‐Blackwell; 2010. p. 60.1‐60.12. 2. Garg S, Baveja S. Generalized granuloma annulare treated with monthly rifampicin, ofloxacin, and minocycline combination therapy. Indian J Dermatol2013;58:197‐9. 3. Naveen KN, Pai VV, Athanikar SB, Gupta G, Parshwa...

We present the case of a woman of 40 years of age with a history of obesity, systemic hypertension, and migraine, and who was on treatment with clorthalidone, propanolol, and rizatriptan. She was seen for a clearly delimited hypopigmented macule on the lateral aspect of the left thigh and lower leg, following the path of a varicose vein (Figure 1). The lesion appeared on an area of previously h...

Introduction: The sparing of the involvement of a cutaneous disease in a site that has been previously subjected to a skin disease, congenital nevus or physical insult has been reported in literature by various names, including the inverse Koebner phenomenon. Objectives: To review cases that we have seen and to document the reported cases and unify them with a single term, the “Sparing phenomen...

RATIONALE Trauma or surgical incision might cause Koebner phenomenon (KP) in patients with cutaneous diseases, but seldom studies reported KP induced by repeated orthopedic surgery. PATIENT CONCERNS The 22-year-old man did not have any prior histories of cutaneous diseases. Two months after the revision surgery for nonunion of the left femoral shaft fracture, KP was noted by psoriasis present...

Over 30% of diabetic patients develop skin conditions during the course of their disease. The following can occur: a) diseases such as scleredema, bullosis diabeticorum (diabetic bullae), granuloma annulare, waxy skin with limited joint mobility of the fingers, finger pebbling, eruptive xanthomas, yellow skin, and diabetic dermopathy; b) bacterial infections, such as erythrasma, necrotizing fas...

Lichen sclerosus (LS) is a chronic benign inflammatory disorder of skin and mucosa which affects patients of all age groups, sex and race, particularly caucasian prepubertal girls and postmenopausal women. The etiology of LS is unknown, but it has been suggested that genetic predisposition to inflammatory disorders, immunological constitutions, hormonal influences and local factors might play a...