نتایج جستجو برای: rev 1

تعداد نتایج: 2765708  

Journal: :Thorax 2011
Ailsa Lyons John Britton

places spreads to other countries. BMJ 2011;342:d617. 13. Hajek P, Stead LF, West R, et al. Relapse prevention interventions for smoking cessation. Cochrane Database Syst Rev 2005;(1):CD003999. 14. Richardson L, Hemsing N, Greaves L, et al. Preventing smoking in young people: a systematic review of the impact of access interventions. Int J Environ Res Public Health 2009;6:1485e514. 15. Stead LF...

Journal: :RNA 2014
Isabel Nawroth Florian Mueller Eugenia Basyuk Nancy Beerens Ulrik L Rahbek Xavier Darzacq Edouard Bertrand Jørgen Kjems Ute Schmidt

The HIV-1 Rev protein mediates export of unspliced and singly spliced viral transcripts by binding to the Rev response element (RRE) and recruiting the cellular export factor CRM1. Here, we investigated the recruitment of Rev to the transcription sites of HIV-1 reporters that splice either post- or cotranscriptionally. In both cases, we observed that Rev localized to the transcription sites of ...

Journal: :AIDS Research and Therapy 2006
Alessandro Michienzi Fernanda G De Angelis Irene Bozzoni John J Rossi

The Rev protein of the human immunodeficiency virus (HIV) facilitates the nuclear export of intron containing viral mRNAs allowing formation of infectious virions. Rev traffics through the nucleolus and shuttles between the nucleus and cytoplasm. Rev multimerization and interaction with the export protein CRM1 takes place in the nucleolus. To test the importance of Rev nucleolar trafficking in ...

Journal: :Journal of cell science 1996
M Dundr G H Leno N Lewis D Rekosh M L Hammarskjöid M O Olson

The HIV-1 Rev protein localizes predominantly to the nucleolus of HIV-1-infected or Rev-expressing cells. The subcellular location of Rev during mitotic nucleolar disintegration was examined at various stages of mitosis in synchronized Rev-expressing CMT3 cells. During early prophase Rev was predominantly located in disintegrating nucleoli and began to accumulate at the peripheral regions of ch...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1990
L S Tiley P H Brown S Y Le J V Maizel J E Clements B R Cullen

Visna virus is an ungulate lentivirus that is distantly related to the primate lentiviruses, including human immunodeficiency virus type 1 (HIV-1). Replication of HIV-1 and of other complex primate retroviruses, including human T-cell leukemia virus type I (HTLV-I), requires the expression in trans of a virally encoded post-transcriptional activator of viral structural gene expression termed Re...

Journal: :Journal of virology 1990
S Schwartz B K Felber D M Benko E M Fenyö G N Pavlakis

We have used the polymerase chain reaction technique to clone the small multiply spliced mRNA species produced after infection of human cells by a molecular clone of human immunodeficiency virus type 1 (HIV-1). We identified six Rev-expressing mRNAs, which were generated by the use of two splice acceptors located immediately upstream of the rev AUG. The class of small mRNAs included 12 mRNAs ex...

2015
Tracy E. Schmidt ELLEN SCHMIDT

The nucleolus is a plurifunctional organelle with dynamic protein exchange involved in diverse aspects of cell biology. Additionally, the nucleolus has been shown to have a role in the replication of numerous viruses, which includes HIV-1. Several groups have reported HIV-1 vRNA localization within the nucleolus. Moreover, it has been demonstrated the HIV-1 Rev protein localizes to the nucleolu...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید