نتایج جستجو برای: retinol binding protein

تعداد نتایج: 1449573  

Journal: :The Journal of Clinical Endocrinology & Metabolism 2007

Journal: :Critical Reviews in Biochemistry and Molecular Biology 2020

Journal: :Journal of Biological Chemistry 1987

Journal: :Molecular and cellular biology 2012
Julie Norseen Tetsuya Hosooka Ann Hammarstedt Mark M Yore Shashi Kant Pratik Aryal Urban A Kiernan David A Phillips Hiroshi Maruyama Bettina J Kraus Anny Usheva Roger J Davis Ulf Smith Barbara B Kahn

Retinol-binding protein 4 (RBP4), the sole retinol transporter in blood, is secreted from adipocytes and liver. Serum RBP4 levels correlate highly with insulin resistance, other metabolic syndrome factors, and cardiovascular disease. Elevated serum RBP4 causes insulin resistance, but the molecular mechanisms are unknown. Here we show that RBP4 induces expression of proinflammatory cytokines in ...

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