Purpose To describe the clinical course of a patient with non-infectious idiopathic unilateral panuveitis and retinal vasculitis treated with subcutaneous repository adrenocorticotropic hormone (ACTH) gel. Observations A 33-year-old male presented with blurry vision and floaters in the left eye (OS). The best-corrected visual acuity was 20/20 in the right eye (OD) and 20/50 in OS at the time ...

Sheemar A, et al. BMJ Case Rep 2017. doi:10.1136/bcr-2017-222596 Description A 13-year-old Indian girl presented with painless vision loss in left eye since 3 months which was gradual in onset. She had been treated with intravenous steroids for optic neuritis 2 months earlier when her visual acuity had improved from 20/200 to 20/20 in left eye. Currently, she complained of recurrent episodic vi...

an ERM and CNV on initial examination. However, the results of a fundus examination in our patients did not reveal any clinical signs of CNV before ERM surgery. In addition, 1 patient (case 2) underwent FA 1 month after ERM removal, which showed no hyperfluorescence in the macula. We do not believe FA is necessary before performing ERM removal to rule out preexisting CNV. However, FA is valuabl...

OBJECTIVES To evaluate the clinical response after switching from infliximab to adalimumab in patients with Behçet's disease (BD). METHODS In this ongoing, prospective, longitudinal and observational study, data were collected on efficacy and safety of every patient with BD beginning anti-TNF therapy in the last 8 years. The present analysis was restricted to patients who were switched to ada...

Perivasculitis is a common pathological reaction in the retina, the veins being affected more frequently than the arteries. It is not a specific disease entity and the majority of cases are thought to result from an allergic reaction to one of a wide variety of antigens (Ashton, I962). Reviews of the subject have been published by Donders (I958), GoddeJolly (I96I), Doden (I963), Koliopoulos (i9...

Retinal vessels may be affected by inflammatory processes of various origins, usually within the context of uveitis. Retinal vasculitis can lead to vascular occlusion and/or rupture of the blooderetinal barrier, and therefore can be the cause of severe visual loss. Retinal vasculitis is usually defined by the presence of ophthalmoscopically visible whitish perivascular infiltrates. Veins are mo...

Twenty-six patients (39 eyes) with retinal neovascularisation associated with ocular inflammation were identified from the retinal vasculitis clinic at St Thomas's Hospital. Eight patients had sarcoidosis, seven patients Behçet's disease, and 11 had idiopathic retinal vasculitis. Twenty-three patients had required systemic therapy to control the inflammation and 11 patients received laser photo...

A patient with HIV and syphilis presents with bilateral retinal vasculitis and recurrent vitreous hemorrhage. Diagnostic and treatment strategies are discussed.

PURPOSE To describe a rare branch retinal vein occlusion (BRVO) followed by central retinal artery occlusion (CRAO) in a patient with Churg-Strauss syndrome (CSS). METHODS A 55-year-old man with a not yet diagnosed CSS developed a BRVO in the left eye and 1 year later a CRAO with painless and acute vision loss in the same eye. Medical history included bronchial asthma, history of allergy, eos...

PURPOSE To report a case of idiopathic retinal vasculitis, aneurysms and neuroretinitis (IRVAN) syndrome associated with positive perinuclear antineutrophil cytoplasmic antibody (P-ANCA). CASE REPORT A 51-year-old man presented with loss of vision in his right eye since many years ago and blurred vision in his left eye over the past year. Ophthalmologic examination revealed optic atrophy and ...