purpose: to study recordings of oscillatory potentials (ops) of the electroretinogram (erg) in diabetic eyes that have no visible fundus alterations, to ascertain whether changes in sensitivity are evident when compared with recordings from age-matched controls. methods: ops of the erg were measured from 68 eyes of 34 patients with diabetes without retinopathy and from 30 eyes of 15 normal subj...

PurposeAbusive head trauma (AHT) is the leading cause of infant death and long-term morbidity from injury. The ocular consequences AHT are controversial, pathophysiology retinal research findings still not clearly understood. It has been postulated that vitreoretinal traction plays a major role in findings. A computer simulation model was developed to evaluate determine whether distribution for...

Bassoon (BSN) is a presynaptic cytomatrix protein ubiquitously present at chemical synapses of the central nervous system, where it regulates synaptic vesicle replenishment and organizes voltage-gated Ca2+ channels. In sensory photoreceptor synapses, BSN additionally plays decisive role in anchoring ribbon, organelle functional extension active zone, to membrane. this study, we functionally str...

Vesicular transporters regulate the amount and type of neurotransmitter sequestered into synaptic vesicles and, hence, the kind of signal transmitted to postsynaptic neurons. Glutamate is the prominent excitatory neurotransmitter in retina; GABA and glycine are the main inhibitory neurotransmitters. Little is known about the ontogeny of vesicular neurotransmission in retina. We investigated exp...

To test tuning methods for the Retina Encoder RE of a Retina Implant RI as a visual prosthesis for blind subjects with retinal degenerations a suitable simulation of the patient s evaluative response to RE state al terations must be provided RE simulates real time retinal information processing and consists of several hundreds of spatio temporal receptive eld RF lters to generate electrical sig...