We consider the task of dimensionality reduction for regression (DRR) informed by realvalued multivariate labels. The problem is often treated as a regression task where the goal is to find a low dimensional representation of the input data that preserves the statistical correlation with the targets. Recently, Covariance Operator Inverse Regression (COIR) was proposed as an effective solution t...

BACKGROUND AND AIMS It is not yet understood how attitudes concerning dementia risk may affect motivation to change health behaviours and lifestyle. This study was designed to develop a reliable and valid theory-based measure to understand beliefs underpinning the lifestyle and health behavioural changes needed for dementia risk reduction. METHODS 617 participants aged ≥50 years completed a t...

In steroid-naive asthmatics, airway hyperresponsiveness correlates with noninvasive markers of airway inflammation. Whether this is also true in steroid-treated asthmatics, is unknown. In 31 stable asthmatics (mean age 45.4 yrs, range 22-69; 17 females) taking a median dose of 1,000 microg inhaled corticosteroids (ICS) per day (range 100-3,600 microg x day(-1)), airway responsiveness to the "di...

Deficit Round Robin (DRR) is probably the most scalable fair-queueing packet scheduler. Unfortunately, it suffers from high delay and jitter with respect to a perfectly fair (and smooth) service. Schedulers providing much better service guarantees exist, but have a higher computational cost. In this paper we deal with this issue by proposing a modification scheme for reducing the amortized exec...

Recent behavioral and electrophysiological studies have attributed an important role to dorsal root reflexes (DRRs) in the initiation and development of neurogenic inflammation produced by intradermal capsaicin (CAP). The DRRs can occur in peptidergic fibers, resulting in peripheral release of neuromediators that produce vasodilation, plasma extravasation and subsequently hyperalgesia and allod...

Combined input-crosspoint-queued (CICQ) switch structure decouples the inputs and outputs matching and enables totally distributed arbitration. CICQ switch cannot achieve 100% throughput under nonuniform traffic if Round-Robin (RR-RR) algorithm is used. The other existing schemes require quite a bit of hardware and time complexity. In this paper, we theoretically prove that the RR-RR can achiev...

Tumor hypoxia contributes to a biologically aggressive phenotype and therapeutic resistance. Recent studies have revealed that hypoxia reduces expression of several DNA damage recognition and repair (DRR) genes via both hypoxia-inducible factor (HIF)-independent and -dependent pathways, and this induced genomic instability in cancer cells. We show here that one of the HIF-target genes-different...

In 2D-3D Medical Image Registration (MIR), preoperative 3D CT images are registered with intraoperative 2D X-rays images obtained by fluoroscopy or Electronic Portal Imaging Devices (EPID). 2D-3D MIR is established by computing Digitally Reconstructed Radiograph (DRR) images rendered from the volumetric data and is useful in many medical procedures where surgical planning is undertaken using vo...

This paper applies a Game-based Learning Evaluation Model (GEM) to assess whether the early warning – early action serious game “Ready!” is an effective component to add to existing Disaster Risk Reduction (DRR) training curricula, facilitated by NGO staff and applied at the community level. We developed a paper-based survey with 17 five-level Likert items and 15 open questions addressing the d...

Previous downlink scheduling algorithms of WiMAX (Worldwide Interoperability for Microwave Access), like DRR (Deficit Round-Robin) and WRR (Weighted Round-Robin), usually reserve minimum rate to each type of traffic and cannot consider the status of queue length of each connection, thus making it unsuitable for VoIP on-off traffic model. One well-designed scheduling algorithm is expected to coo...