Hormones must be balanced and dynamically controlled for the Female Reproductive Tract (FRT) to function correctly during menstrual cycle, pregnancy, delivery. Gamete selection successful transfer uterus, where it implants pregnancy occurs, is supported by mucosal epithelial lining of FRT ovaries, cervix, fallopian tubes, vagina. Successful implantation placentation in humans other animals rely...

Neuroendocrine tumors of the female reproductive tract are a heterogeneous group of neoplasms that display various histologic findings and biologic behaviors. In this review, the classification and clinicopathologic characteristics of neuroendocrine tumors of the female reproductive tract are described. Differential diagnoses are discussed, especially for non-neuroendocrine tumors showing high-...

In adult mammals numerous target tissues and organs for estrogens exist. Little is known about possible target organs during embryogenesis other than the reproductive tract and the gonads. This is the first report on the expression of estrogen receptor beta (ERbeta) in comparison with ERalpha mRNA during mouse embryogenesis. We found expression of estrogen receptor mRNA in the reproductive trac...

The male reproductive system (Figure 1) consists of a series of glandular, muscular, and ciliated tubes and diverticula dedicated to the production, storage, nourishment, and activation of spermatozoa, and to their transport into the female reproductive tract. There are three products of the system: the germ cells, the seminal fluid that bathes them when they are emitted, and hormones that regu...

The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductive development and regulates the transcription of steroid-modifying cytochrome P450 genes. We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexual development. In Hr39 mutant females, the sperm-storing spermathecae and glandular parovaria are absent or defect...

OBJECTIVE This study aimed to compare digital camera assessment of the reproductive tract (DART) to colposcopy for the evaluation of abnormal Pap smears. MATERIALS AND METHODS Participants included 207 women with abnormal Pap smears. Colposcopy and DART were performed on each patient by separate examiners with the goal of lesion detection. Analysis was performed per patient and per biopsy. ...

Mature mammalian spermatozoa are quiescent in the male reproductive tract. Upon ejaculation and during their transit through the female reproductive tract, they undergo changes that enable them to fertilize the egg. During this process of capacitation, they acquire progressive motility, develop hyperactivated motility, and are readied for the acrosome reaction. All of these processes are regula...