BACKGROUND The effect of alcohol consumption on prostate health and reproductive hormone profiles has long been investigated and currently, no consensus has been reached. Additionally, large studies focusing on this topic are relatively rare in China. PURPOSE To investigate the association of alcohol consumption with prostate measurements and reproductive hormone profiles in Chinese populatio...

There is global concern regarding the potential impacts of endocrine-disrupting chemicals (EDCs) on the health of wildlife and humans. Exposure to some estrogens, at concentrations found in the environment impairs reproductive function and behavior. However, nearly all work on endocrine disruption has investigated the effects of exposure on individuals and there is an urgent need to understand ...

Reproductive status is tightly coupled to metabolic state in females, and ovarian cycling in mammals is halted when energy output exceeds energy input, a metabolic condition known as negative energy balance. This inhibition of reproductive function during negative energy balance occurs due to suppression of gonadotropin-releasing hormone (GnRH) release in the hypothalamus. The GnRH secretagogue...

Objective Indiscriminate use of synthetic pyrethroid insecticides, Cypermethrin (Cyp) and Deltamethrin (Del) have been reported to cause system toxicity in mammals including humans. The dietary antioxidants protects tissues and organs against insecticides/xenobiotic induced damage. In present study, we evaluated the effect of exposure of Cyp and Del and possible protective roles of curcumin and...

HIGHLIGHTS The proprioceptive system provides a sense of body awareness and detects controls force pressure. Menstruation is the regular, orderly shedding uterine wall, in response to interactions hormones produced by hypothalamus, pituitary, ovaries. Estrogen steroid hormone involved female reproductive organs, as well numerous other biological systems including neuroendocrine, vascular, skele...

Estrogen (E2) plays significant roles in ligand target organs such as the reproductive organs, bone and the brain. This female steroid hormone is well known also to be deeply involved in cancer development in the reproductive organs. The majority of E2 actions are mediated through its nuclear estrogen receptor (ER). ERa and ER~ are members of the steroid/thyroid hormone nuclear receptor superfa...