Rapid coverage and epithelial closure of extensive burns remains a major requirement for patient recovery. Although many skin substitutes have been described, permanent regeneration of both epithelial and connective tissues after a single surgical application of a skin substitute has not become routine. To replace both dermal and epidermal skin, cultured skin substitutes (CSS) were prepared fro...

Vitiligo is an acquired condition that presents as sharply demarcated white macules. It affects 1%-2% people of all races regardless of sex and age. Although the disease does not have any systemic complications, it is of great cosmetic concern, particularly in darker skinned individuals, as in Indians, where it creates psychological problems due to the stigma attached to it. In vitiligo, there ...

The patients with universal vitiligo and residual pigmented patches usually do not benefit from available repigmenting methods and are better scheduled for depigmentation by medical, laser,and or freezing procedures. A 37-year-old lady with universal vitiligo and remaining pigmentation in the left anterior chest wall, ...

Background: Despite great advances in therapeutic regimens,complete repigmentation in vitiligo is still out of reach. The aimof this assay was to study the efficacy and tolerability of repeatedneedling combined with narrowband ultraviolet B (NBUVB)therapy in the treatment of generalized, stable, refractory vitiligo.Method: Twenty-six patients with stable generalized intractablevitiligo were rec...

Background: Vitiligo is an acquired idiopathic pigmentary skin disorder characterized by sharply demarcated milky white macules with variable size and shape. It has an estimated worldwide incidence of 0.5-4% and occurs in half of the patients before the age of 20 years. Since exact pathogenic mechanism is unknown, several proposed hypotheses are alternation of cellular and humoral immunity, mel...

BACKGROUND Only a few clinical trials have been performed on the treatment of generalized vitiligo in children. Recently, narrow-band UVB therapy has been reported to be an effective and safe therapeutic option in adult patients with vitiligo. OBJECTIVE We studied the efficacy and safety of UVB (311 nm) therapy in children with generalized vitiligo and evaluated the effect of the therapy on t...

Vitiligo is a common acquired depigmentation disorder for which many treatments have previously been used with varying effects. The aim of the present study was to evaluate the efficacy and safety of targeted high-intensity (TH) and narrow band (NB) ultraviolet B light (UVB) for vitiligo treatment. A total of 33 patients with vitiligo were enrolled in the present study. Patients with a symmetri...

INTRODUCTION There are various treatment modalities to remove the black patches of melanin pigmentation. The aim of the study is to clinically compare the diode laser ablation and surgical stripping technique for gingival depigmentation and to evaluate their effect on the histological changes in melanocyte activity. MATERIALS AND METHODS A total of 40 sites of 20 patients with bilateral melan...

The speaker gave a brief review of published reports on the medical therapy of vitiligo in the last five years. First of all, the use of topical agents was discussed. Fifty percent of the patients had more than 75% of their lesions repigmented after 0.1% tacrolimus treatment. The efficacy was comparable to clobetasol propionate. There was limited data on pimecrolimus but a trial showed that its...