نتایج جستجو برای: remission maintenance therapy

تعداد نتایج: 804901  

2014
Fernando Magro Rami Eliakim

In the last 15 years or so anti-tumor necrosis factor (TNF) treatment has gained popularity, and concepts such striving for endoscopic remission and biomarkers remission (“deep remission”) are becoming upfront issues. Anti-TNF treatment is given for years and safety and economic issues are raised as well. Th e questions when to stop anti-TNF therapy and how to deal with the patient relapses are...

Journal: :Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society 2015
Takahiro Beppu Yoichiro Ono Toshiyuki Matsui Fumihito Hirai Yutaka Yano Noritaka Takatsu Kazeo Ninomiya Kozue Tsurumi Yuho Sato Haruhiko Takahashi Yuuki Ookado Akihiro Koga Ken Kinjo Takashi Nagahama Takashi Hisabe Yasuhiro Takaki Kenshi Yao

BACKGROUND AND AIM The aim of the present study was to endoscopically evaluate ileal mucosal healing during maintenance therapy with infliximab in order to investigate the clinical significance of endoscopic examination of ileal lesions in Crohn's disease patients. METHODS This study retrospectively analyzed 54 patients who mainly had active ulcers of the ileum on endoscopy at baseline who we...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2017
Arnaud Pigneux Marie C Béné Philippe Guardiola Christian Recher Jean-Francois Hamel Mathieu Sauvezie Jean-Luc Harousseau Olivier Tournilhac Francis Witz Christian Berthou Martine Escoffre-Barbe Denis Guyotat Nathalie Fegueux Chantal Himberlin Mathilde Hunault Martine Delain Bruno Lioure Eric Jourdan Frederic Bauduer Francois Dreyfus Jean-Yves Cahn Jean-Jacques Sotto Norbert Ifrah

Purpose Elderly patients with acute myeloid leukemia (AML) have a poor prognosis, and innovative maintenance therapy could improve their outcomes. Androgens, used in the treatment of aplastic anemia, have been reported to block proliferation of and initiate differentiation in AML cells. We report the results of a multicenter, phase III, randomized open-label trial exploring the benefit of addin...

2014
Sine Schnoor Buhl Casper Steenholdt Jørn Brynskov Ole Østergaard Thomsen Klaus Bendtzen Mark Andrew Ainsworth

INTRODUCTION Infliximab (IFX), a monoclonal chimeric antibody against tumour necrosis factor (TNF) α, is effective for induction and maintenance of remission in moderate to severe Crohn's disease. Discontinuation of IFX maintenance therapy in patients in remission should be considered in order to reduce the potential long-term side effects and lower costs. METHODS AND ANALYSIS This is a prosp...

Journal: :Haematologica 2012
Harry Iland Ken Bradstock John Seymour Mark Hertzberg Andrew Grigg Kerry Taylor John Catalano Paul Cannell Noemi Horvath Sandra Deveridge Peter Browett Tim Brighton Li Chong Francisca Springall Juliet Ayling Alberto Catalano Shane Supple Marnie Collins Juliana Di Iulio John Reynolds

BACKGROUND Initial therapy for patients with acute promyelocytic leukemia most often involves the combination of all-trans-retinoic acid with anthracycline-based chemotherapy. The role of non-anthracycline drugs in induction and consolidation is less well-established and varies widely between different cooperative group protocols. DESIGN AND METHODS In an attempt to minimize relapse and maxim...

Journal: :Medicine 2014
Jason Springer Benjamin Nutter Carol A Langford Gary S Hoffman Alexandra Villa-Forte

To determine outcomes in relation to duration of maintenance therapy in patients with granulomatosis with polyangiitis (Wegener's) (GPA), we conducted a retrospective chart review of patients with GPA seen at a single vasculitis center from 1992 to 2010. All patients achieved remission defined by a Birmingham Vasculitis Activity Score for Wegener Granulomatosis (BVAS/WG) of 0 with either cyclop...

2011

Around 2–4 in 1,000 people in Northern Europe have ulcerative colitis or Crohn’s disease (Rubin 2000). Both are chronic, relapsing, inflammatory disorders of the gastrointestinal tract with several shared clinical features, but with largely distinct risk factors, genetic, immunological, anatomical and histological features, and response to therapy (DTB 2003). Their treatment, which includes med...

2014

Around 2–4 in 1,000 people in Northern Europe have ulcerative colitis or Crohn’s disease (Rubin 2000). Both are chronic, relapsing, inflammatory disorders of the gastrointestinal tract with several shared clinical features, but with largely distinct risk factors, genetic, immunological, anatomical and histological features, and response to therapy (DTB 2003). Their treatment, which includes med...

Journal: :iranian journal of toxicology 0
مرتضی رهبر طارمسری morteza rahbar taramsari department of forensic medicine and toxicology, guilan university of medical sciences, rasht, iran. علیرضا بادسار alireza badsar department of forensic medicine and toxicology, guilan university of medical sciences, rasht, iran. سیاوش فلاحتکار , siavash falahatkar department of urology, guilan university of medical sciences, rasht, iran. هادی موثق hadi movassagh medical student of guilan university of medical science, rasht, iran. مرتضی فلاح کارکان morteza fallah karkan medical student of guilan university of medical science, rasht, iran. سینا منتظری sina montazeri medical student of guilan university of medical science, rasht, iran. حمیدرضا مولازاده

background: methadone is considered a long-acting opioid agonist which is widely used in the treatment of drug addiction. it is believed that opioids can cause erectile dysfunction (ed) by inhibiting gonadotropin and testosterone release. this study is aimed at defining the possible effects of conservative treatment with methadone on erectile dysfunction in the addicts. methods: a total of 382 ...

Journal: :Arquivos de gastroenterologia 2013
Alvaro Mitsunori Nishikawa Luciano Paladini Régis Delfini Paulo Gustavo Kotze Otavio Clark

CONTEXT Unspecified Ulcerative Rectocolitis is a chronic disease that affects between 0.5 and 24.5/105 inhabitants in the world. National and international clinical guidelines recommend the use of aminosalicylates (including mesalazine) as first-line therapy for induction of remission of unspecified ulcerative rectocolitis, and recommend the maintenance of these agents after remission is achiev...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید