RESULTS: The release of NGF from the conduit was within the concentration range of 0.5~10 ng/ml/day (n=5) without an initial burst. The released NGF stimulated in vitro neurite growth of cultured DRGs (823.4 ± 24.3 μm using day 28 release sample) comparable to fresh NGF (845.7 ± 25.7 μm using 10 ng/ml fresh NGF) (p>0.05), demonstrating that the released NGF from the conduit at 37°C for 4 weeks ...

At concentrations between 1 to 10 mM, caffeine reduced the Ca-accumulating capacity of fragmented reticulum obtained from frog and rabbit muscle. With 8 mM caffeine enough Ca was released from frog reticulum to account for the force of the contracture. Caffeine did not affect all reticulum membranes equally. The fraction which was spun down at 2000 g was more sensitive than the lighter fraction...

On the basis of mass balance calculations performed for nitrogen (N) uptake experiments in the Southern California Bight (SCB), it has been suggested that a significant portion of dissolved inorganic N (DIN) uptake results in the production of dissolved organic N (DON). To investigate this process, the fate of ammonium (NH4 ) and nitrate (NO3 ) uptake was quantified within the euphotic zone at ...

This study investigated the effects of increasing mercury (Hg) concentration on early developmental stages of sea urchin, Echinomethra mathaei, as a bioindicator. The toxicity test was carried out after the gamete released induction and fertilization in six concentrations of mercury within the range of 4, 8, 16, 32, 64 and 128 µg/L. Embryos samples were incubated for 30 h in control and test so...

Electricity Released from Matter: DR. KARL K. Scientific Apparatus and Laboratory Methods: DARROW .................. ...;.i........... ...... 591 Mouth Pipette and Containers for Smaller OrThe Electron Theory of Metallic Conduction: PRoganisms: EARL H. MYERS. Microscope Lamp for FESSOR J. C. SLATER ... . . . 595 Biological Laboratories: DR. RICHARD M. HOLMAN 609 Obituary: Special Articles: Fred...

studies with CLL and MCL have provided support for this explanation (Buchner et al11; M. F. M. de Rooij, J. J. Buggy, and M.S., manuscript in preparation). In this perspective, it is tempting to speculate that combining these agents with anti-CD47 may turn out to be a highly efficacious treatment for NHL patients: once the malignant B cells have been forced out of their protective growthand sur...

OBJECTIVE The aims of this study were to quantify the extent of volatilization from 131I-NaI therapeutic capsules prepared in a centralized radiopharmacy and to quantify the amount of volatile 131I released from a dispensing vial containing a compounded 131I-NaI therapy capsule. METHODS Therapy capsules were prepared by injecting 131I oral solution into capsules containing anhydrous dibasic s...

We have recently reported that human natural killer (NK) cells release exosomes that express both NK-cell markers and cytotoxic molecules. Similar results were obtained with circulating exosomes from human healthy donors. Both NK-cell derived and circulating exosomes exerted a full functional activity and killed both tumor and activated immune cells. These findings indicate that NK-cell derived...

The widespread use of silver nanoparticles (Ag-NPs) in commercial products, especially textiles, will likely result in an unknown spread of Ag into the environment. The quantification and characterization of the Ag released from nano-Ag-products is an important parameter needed to predict the effect of Ag-NPs on the environment. The aim of this study was to determine the amount and the form of ...