The present study deals with development of a floating in-situ gel of the narrow absorption window drug baclofen. Sodium alginate-based in-situ gelling systems were prepared by dissolving various concentrations of sodium alginate in deionized water, to which varying concentrations of drug and calcium bicarbonate were added. Fourier transform infrared spectroscopy (FTIR) and differential scannin...

the purpose of this study was to develop a new monolithic matrix tablet to completely deliver glipizide in a zero order manner over a sustained period. two approaches were examined using drug in a formulation that contain polymer like hydroxylpropyl methyl-cellulose k 100 (hpmck) and eudragit l 100. the granules were prepared by wet granulation method and thereby formulated as f-1, f-2. f-3 and...

Background and purpose: dye is widely used in industries such as cosmetic, leather, paper and textile and release to the environment via their effluents. The purpose of this study was to compare the efficiency of low-cost adsorbents in acid orang 7 dyes removal from water. Materials and Methods: The Rice Stem biomass was sun dried, crushed and sieved to particle sizes in range of 1-2 mm. Then ...

Silica aerogels are porous and extremely lightweight nano-materials shows interesting properties. These materials, because of biocompatibility, non-harmful to the body and special physical characteristics such as large surface area and low density have great potential for use in a drug delivery system (DDS). The focus of this study is the evaluation of the effects of silica aerogels on improvin...

Pyrolysis essentially is the thermal decomposition of organic matter under inert atmospheric conditions or in a limited supply of air, leading to the release of volatiles and formation of char. Modeling of pyrolysis implies the representation of the chemical and physical phenomena in a mathematical form. In this study, Differential Evolution (DE) algorithm is applied and global optimum set of k...

Pyrolysis is the thermal decomposition of organic matter under inert atmospheric conditions, leading to the release of volatiles and formation of char. It is also a first step in the biomass gasification. Understanding of kinetic parameters is essential for the design of a suitable pyrolysis reactor. In the proposed kinetic model of this study, the kinetic scheme of biomass decomposition by two...

The effect of oleic acid (5 and 10% v/v) and xanthan gum (0.5 and 1% wt) on  partitioning and retention of ethyl acetate and diacetyl from two matrices with a different composition was investigated by applying static head space gas chromatography. Two matrices with different composition have been developed: one containing carbohydrates (xanthan gum) and in the second one, called co...

in this study, an in-house multi-dimensional code has been developed which simulates the combustion of n-heptane in a homogeneous charge compression ignition (hcci) engine. it couples the flow field computations with detailed chemical kinetic scheme which involves the multi-reactions equations. a chemical kinetic scheme solver has been developed and coupled for solving the chemical reactions an...

this study is focused on the development of a systematic computational approach which implements genetic algorithm (ga) to find the optimal rigorous kinetic models.a general kinetic model for hydrogenolysis of dibenzothiophene (dbt) based on langmuir-hinshelwood type has been obtained from open literature. this model consists of eight continuous parameters(e.g., arrhenus  and van't hoff paramet...