background: vascular endothelial growth factor (vegf) has a key role in angiogene-sis and in transplantation. the level of vegf is related to the differences in the dna sequence of its promoter region. objectives: in this study, the association between the combination of vegf –1154 g and –2578 c alleles and vegf production by lps-stimulated pbmcs was investigated. in addition; the relationship ...

Let I = [a, b] and let X be a normed space. A function f : I → X is said to be regulated if for all t ∈ [a, b) the limit lims→t+ f(s) exists and for all t ∈ (a, b] the limit lims→t− f(s) exists. We denote these limits respectively by f(t ) and f(t−). We define R(I,X) to be the set of regulated functions I → X. It is apparent that R(I,X) is a vector space. One checks that a regulated function is...

High levels of regulated oncogen-alpha (GRO-a) expression have been observed in the liver. GRO-a stimulates proliferation of epithelial cells and induction of rolling and extravascular migration of neutrophils and mononuclear cells. Given the above observations, this chemokine was chosen to be analyzed in freshly isolated and cultured hepatocytes. In this study, hepatocytes (2×106 cell/ml) were...

background alcoholic hepatitis (ah) is an acute manifestation of alcoholic liver disease with high mortality rates. objectives our aim was to study the molecular mechanisms of ah. materials and methods the differentially expressed genes (degs) in liver between ah and control cases were identified by analyzing the gse28619 microarray data using t-test. the kyoto encyclopedia of genes and genomes...

introduction: gtpase regulator associated with focal adhesion kinase (graf) is a recently identified gtpase activating protein that has the tumor suppressor properties. however, the expression level of graf in leukemia had received less attention. the main purpose of this research was the evaluating of the expression level of graf in patients with acute myeloid leukemia (aml). materials and met...

A conventional high power DC power supply systems consist of a three-phase diode rectifier followed by a high frequency converter to supply loads at regulated DC voltage. These rectifiers draw significant harmonic currents from the utility, resulting in poor input power factor. In this paper, a DC power supply based on dual-bridge matrix converter (DBMC) with reduced number of switches is p...

variety of energy–ecology optimizing means that optimum result of fuel combustion is focused not only on the direct efficiency of its usage but also on minimum environmental damage. best possible fuel combustion connected with controlled level of chemical underburn is considered to be one of the simpliest, cheapest and the most effective methods of optimizing. it is essential to notice that the...

A Central nervous system (CNS) hemorrhage is bleeding in or around the brain and spinal cord. Reasons of CNS hemorrhage include high blood pressure, cancers, drug abuse, abnormally weak blood vessels that leakage, and trauma. Regression of CNS bleeding was confirmed to be relatively repetitive in patients with severe FV, FX, FVII and FXIII deficiencies. Generally in CNS hemorrhage, radiological...

objective(s): hypoxia is a serious challenge for treatment of solid tumors. this condition has been manifested to exert significant therapeutic effects on glioblastoma multiform or (who) astrocytoma grade iv. hypoxia contributes numerous changes in cellular mechanisms such as angiogenesis, metastasis and apoptosis evasion. furthermore, in molecular level, hypoxia can cause induction of dna brea...