BACKGROUND Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder characterized by the Philadelphia chromosome generated by the reciprocal translocation t(9: 22)(q34;q11). CML is usually diagnosed in the chronic phase. Blast crisis represents an advanced phase of CML. Extramedullary blast crisis as the initial presentation of CML with bone marrow remaining in chronic phase is an...

Over the past two decades, financial market crises with similar features have occurred in different regions of the world. Unstable cross-market linkages during a crisis are referred to as financial contagion. We simulate crisis transmission in the context of a model of market participants adopting various strategies; this allows testing for financial contagion under alternative scenarios. Using...

Up until the recent crisis, the Southeast Asian region had been regarded as one of the most dynamic regions in the global economy. Their industrial structures have undergone a process of adjustment into more capital-intensive and technologically sophisticated manufacturing sectors. These adjustments created intra-regional flows of foreign direct investment (FDI) followed by the expansion of cap...

We employ the UTIP data set on the evolution of earnings inequality in manufacturing in the global economy to illuminate two questions. First, do regional patterns of similarity in the movement of large macroeconomic aggregates, such as real GDP, imply underlying similarities of industrial structure, so that knowledge of one national economy in a GDP cluster can reasonably be assumed to convey ...

Introduction Various serotypes of DF were frequently reported in different regions of Pakistan on smaller scale. However, the worst dengue outbreak in Pakistan was experienced in 2011 in Lahore which is a 2nd most popolous city of Pakistan and capital of province punjab. This epidemic erupted during the post monsoon season and claimed 301 lives in just 4 months. To address that health crisis, G...

Current accounts of spatial cyberinfrastructure development tend to overemphasize technologies to the neglect of critical social and cultural issues on which adoption depends. Spatial cyberinfrastructures will have a higher chance of success if users of many types, including nonprofessionals, are made central to the development process. Recent studies in the history of infrastructures reveal ke...