Prognosis of peripheral artery disease (PAD), especially critical limb ischemia, is very poor despite the development of endovascular therapy and bypass surgery. Many patients result in leg amputation and, therefore, vascular regenerative therapy is expected in this field. Gene therapy using vascular endothelial growth factor is the first step of vascular regenerative therapy, but did not confi...

Regenerative medicine would be the most exciting area in the recent scientific topics. In the history of human gene therapy, the severe combined immunodeficiency caused by the absence of adenosine deaminase (SCID-ADA) was the first monogenic disorder for which gene therapy was developed in 1990. Over 30 patients have been treated worldwide using the current protocols, and recent trials provided...

results afscs have the potential to be used in tissue repair and regeneration of bladder and kidney injuries, for the treatment of congenital anomalies like tracheal anomalies and spina bifida therapy etc. however, like other treatment, afscs also have some limitations such as low rate of differentiation of transplanted afscs and immune rejection. conclusions afscs have great therapeutic potent...

Regenerative therapy has been introduced in the literature for a long time and is currently being practiced different fields, including dentistry endodontics. Many applications have reported stem cell therapy. However, many complications adverse events were this context. The present review sheds more light on clinical of regenerative endodontics future perspectives field. There are no doubts th...

The number of clinical trials in regenerative medicine is burgeoning, and stem cell/tissue engineering technologies hold the possibility of becoming the standard of care for a multitude of diseases and injuries. Advances in regenerative biology reveal novel molecular and cellular targets, with potential to optimize tissue healing and functional recovery, thereby refining rehabilitation clinical...

It has always been an ambitious goal in medicine to repair or replace morbid tissues for regaining the organ functionality. This challenge has recently gained momentum through considerable progress in understanding the biological concept of the regenerative potential of stem cells. Routine therapeutic procedures are about to shift towards the use of biological and molecular armamentarium. The p...