background: the prevalence of migraine headaches significantly increased in girls after menarche. this indicated that there is a closely relation between hormonal changes especially the estrogen level with migraine headaches. objectives: the aim of this work was to determine the frequency of migraine and its associated factors in medical students affected with premenstrual syndrome (pms). mater...

how to cite this article: ashrafi mr, najafi z, shafiei m, heidari k, togha m. cinnarizinev ersus topiramate in prophylaxis of migraines among children and adolescents: a randomized, double-blind clinical trial. iran j child neurol. 2014 autumn;8(4): 18-27.   abstract objective migraines, a common health problem in children and adolescents, still do not have an fda approved preventive treatment...

how to cite this article: nejad biglari h, karimzadeh p, mohammadi kord-kheyli m, hashemi sm. migraine types and triggering factors in children. iran j  child neurol 2012;6(2):33-38. objective migraine is a common problem in children and the mean prevalence of migraine in europe among 170,000 adults was 14.7% (8% in men and 17.6% in women) and in children and youth (36,000 participants), the pr...

BACKGROUND Methylergonovine is an ergot alkaloid widely used in postpartum women. It is also an active metabolite of methysergide and previous studies suggest that it could be effective against refractory headache and cluster headache. The purpose of the present study was to assess the potential therapeutic effectiveness of methylergonovine in the emergency treatment of severe migraine. METHO...

Background In many patients suffering from primary headaches, the available pharmacological and behavioural treatments are not satisfactory. This is a review of (minimally) invasive interventions targeting pericranial nerves that could be effective in refractory patients. Methods The interventions we will cover have in common pericranial nerves as targets, but are distinct according to their ra...

background: obesity seems to be associated to migraine headache. increase in body fat, especially in gluteofemoral region, elevates adiponectin and leptin secretion which in turn impair inflammatory processes that could be contributing to migraine risk. this study was designed to assess the relationship between body composition and risk of migraine for the first time. methods: in this cross-sec...

Background/Aims Cyclic vomiting syndrome (CVS) is a disabling migraine variant manifesting as severe episodes of nausea and vomiting and often refractory to many therapies. Gastric electrical stimulation (GES), which can reduce nausea and vomiting in gastroparesis, may provide symptomatic relief for drug-refractory CVS. This study assessed the utility GES in reducing the symptoms of CVS and imp...