BACKGROUND Red blood cell (RBC) alloimmunization is a major immunologic risk of transfusion. However, RBC storage facilitates white blood cell (WBC) apoptosis and apoptotic cells have immunomodulatory properties. We investigated the behavior of WBCs, and apoptosis in particular, in RBC units during storage and then studied the impact of WBC apoptosis on the modulation of posttransfusion alloimm...

An epidemiological survey of haemoparasitic infection in trade cattle was carried out at Lafenwa abattoir, Abeokuta, from August to November 2008. Thin Blood film and Haematocrit Centrifugation Techniques were used detect haemoparasites. A total 452 that comprised 174 cows 278 bulls examined. The breeds included 78 'Red Bororo', 14 'Sokoto Gudali' 360 'White Fulani'. Packed cell volume (PCV), r...

When red blood cells (RBCs) move through narrow capillaries in the microcirculation, they deform as they flow. In pathophysiological processes such as sickle cell disease and malaria, RBC motion and flow are severely restricted. To understand this threshold of occlusion, we use a combination of experiment and theory to study the motion of a single swollen RBC through a narrow glass capillary of...

We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which lead to accurate mechanical properties of realistic RBCs. Based on a semi-analytic theory linear and nonlinear elastic properties of the RBC membrane can be matched with those obtained in optical tweezers stretching experiments. In addition, we develop a nearly stress-free model which avoids a number of ...

BACKGROUND Red blood cell (RBC) transfusion can be lifesaving. However, in many clinical cases, including acute coronary syndromes, percutaneous coronary interventions (PCI), cardiac surgery, and acute critical care, detrimental effects (excess death and myocardial infarction [MI], and also lung infections) have been observed in patients after a RBC transfusion. AIM To evaluate the long-term ...

background: arsenic is one of the most toxic metalloids. anemia and leukopenia are common results of poisoning with arsenic, which may happen due to a direct hemolytic or cytotoxic effect on blood cells. the aim of this study was to examine the effects of hydroalcoholic extract of nasturtium officinale on blood cells and antioxidant enzymes in rats exposed to sodium (meta)arsenite. methods: 32 ...

Materials and methods: Couples who intend to marry have to undergo these tests as part of a compulsory countrywide program. In this study, the red blood cell (RBC) indices among the study population were measured with an electronic cell counter (Sysmex K800). Th e survey involved the measurement of 2 RBC indices, mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH), and the resul...

Objective: To review the published research on allogeneic red blood cell (RBC) and plasma transfusions in children over 4 months of age. Evidence: Search of MEDLINE database between January 1966 and July 1996 and manual search of relevant textbooks. Articles addressing guidelines for administration, evaluation of appropriateness of therapy, utilization and indications for transfusion were selec...

Background: Arsenic is one of the most toxic metalloids. Anemia and leukopenia are common results of poisoning with arsenic, which may happen due to a direct hemolytic or cytotoxic effect on blood cells. The aim of this study was to examine the effects of hydroalcoholic extract of Nasturtium officinale on blood cells and antioxidant enzymes in rats exposed to sodium (meta)arsenite. Methods: 32...