objective the first attack of unprovoked seizure is more frequent than recurrent one and neuroimaging is one of the main parts of the evaluation of these attacks in order to demonstrate the cause and predict the prognosis. the aim of this study was to determine the incidence of abnormal neuroimaging and related factors in children with the first unprovoked seizure. materials & methods a 7-year ...

Deep learning techniques have recently achieved impressive results and raised expectations in the domains of medical diagnosis physiological signal processing. The widely adopted methods include convolutional neural networks (CNNs) recurrent (RNNs). However, existing models possess static connection weights between layers, which might limit generalization capability classification performance a...

Editor's Note: These short, critical reviews of recent papers in the Journal, written exclusively by graduate students or postdoctoral fellows, are intended to summarize the important findings of the paper and provide additional insight and commentary. For more information on the format and purpose of the Journal Club, please see Review of Toyoda et al. Temporal lobe epilepsy (TLE) is the most ...

This study aims to understand seizure control outcomes and the risk of developing new wake seizures (WS) related to the different types of pure sleep epilepsies (SE), which is important in making rational management plans. A retrospective review of the Yonsei Epilepsy Clinic Registry identified 63 patients with pure SE not belonging to any specific epileptic syndromes. They were divided into th...

This study was undertaken to observe the effect of acute stress on seizure occurrence in chronic period of epileptic model rats. Lithium-pilocarpine (LiCl-PILO)-induced epileptic rat model was constructed. At the spontaneous recurrent seizure period, acute stress stimulations such as cat's urine and foot electrical shock were applied to observe the behavioral changes and seizure occurrence. The...

For centuries, extracts of Acorus gramineus have been used extensively in traditional Chinese medicine for the treatment, management, and/or control of human ailments, including central nervous system disorders such as convulsions and epilepsy. In the present study, we investigated the anticonvulsant activity of chronic treatment with the plant's major essential oil component (a-asarone, 50-200...

BACKGROUND AND PURPOSE Developmental and seizure outcomes in patients with cryptogenic West syndrome are variable. Our aim was to clarify the relationship between FDG-PET findings in infancy and long-term seizure and developmental outcome in cryptogenic West syndrome. MATERIALS AND METHODS From 1991 to 1999, we prospectively performed FDG-PET from the onset of cryptogenic West syndrome in 27 ...

Exact low-resolution brain electromagnetic tomography (eLORETA) is a technique for three-dimensional representation of the distribution of sources of electrical activity in the brain. Kurtosis analysis allows for identification of spiky activity in the brain. To evaluate the reliability of eLORETA kurtosis analysis, the results of the analysis were compared with those of equivalent current dipo...

The dentate gyrus continues to produce granule neurons throughout life. Mossy fibers, the axons of granule neurons, undergo atypical sprouting in both clinical and experimental mesial temporal lobe epilepsy. Mossy fiber sprouting (MFS) has been hypothesized to underlie the network reorganization that is thought to produce spontaneously recurring seizures, possibly via the formation of new recur...