Brown tumors are expansile osteolytic lesions of bone, occurring in hyperparathyroidism. They occur more commonly in primary hyperparathyroidism, and tend to regress after the removal of parathyroid adenomas [1]. They are much less common in secondary hyperparathyroidism but have been reported [1]. Brown tumors occur most commonly in ribs , mandible, clavicle, and pelvis, and are uncommon in th...

Introduction: Hyperparathyroidism is presented with increased parathyroid hormone (PTH) secretion due to hyperfunctioning of one or more of the four parathyroid glands. Primary hyperparathyroidism (p-HPT) can be due to parathyroid adenoma, hyperplasia or carcinoma of the parathyroid gland. Secondary hyperparathyroidism (s-HPT) is usually a response to hypocalcaemia and consecut...

parathyroid adenoma involving a single parathyroid gland is the underlying cause of 80-85% of primary hyperparathyroidism (phpt). skeletal system is significantly affected by phpt. brown tumors are known to have affinity for 99mtc-mibi. we report a rare case of phpt presenting with diffuse bony pain, high calcium level and significantly elevated alkaline phosphatase level. 99mtc-pertechnetate/9...

Objective To examine the association between calcium intake and risk of primary hyperparathyroidism in women. Design Prospective cohort study. Setting Nurses’ Health Study I, which originally recruited participants from the 11 most populous states in the United States. Participants 58 354 female registered nurses enrolled in the Nurses’ Health Study I aged 39-66 years in 1986 and with no histor...

Primary hyperparathyroidism is a common condition that affects 0.3% of the general population. Primary and tertiary care specialists can encounter patients with primary hyperparathyroidism, and prompt recognition and treatment can greatly reduce morbidity and mortality from this disease. In this paper we will review the basic physiology of calcium homeostasis and then consider genetic associati...

HYPOTHESIS Total parathyroidectomy without autotransplantation in kidney transplant recipients leads to reduced recurrence rates and similar improvement of clinical symptoms compared with subtotal parathyroidectomy. DESIGN A retrospective cohort study. SETTING University clinic. PATIENTS Thirty-three patients with functioning renal grafts who underwent primary total (n = 17; group 1) or s...

Purpose: This paper evaluates the outcomes of parathyroidectomy for primary hyperparathyroidism with negative localization studies. Methods: All patients preoperative ultrasound and MIBI scan who underwent were retrospectively included. Three groups defined. Group 1 included MIBI. 2 positive 3 Results: In 1, 51% 86% had one adenoma atypical localizations respectively. Unique showed in 87% 93% 3...

UNLABELLED The aim of this report is to describe a fortuitely discovered association between parathyromatosis and papillary thyroid microcarcinoma. CASE DESCRIPTION A 56-year-old woman presented with a pyelic relapsed stone, bone pains, neurovegetative com-plaints and iPTH = 348 ng/l as manifestations of recurrent primary hyperparathyroidism after a right inferior parathyroid adenoma exeresis...