Purpose:Mostwell-differentiatedneuroendocrine tumors (WDNET) of the enteropancreatic system are low-intermediate grade (G1, G2). Elevated proliferation demonstrated by either a brisk mitotic rate (>20/10highpowerfields) orhighKi-67 index (>20%) defines a group of aggressive neoplasms designated as high-grade (G3) neuroendocrine carcinoma (NEC). High-grade NEC is equated with poorly differentiat...

BACKGROUND The relationship between type 1 diabetes mellitus (T1DM) and cancer incidence remains unclear. We sought to assess the all-cause and site-specific cancer incidence in patients with T1DM. METHODS A retrospective cohort study design was employed, in which 14 619 patients with T1DM were retrieved from Taiwan's National Health Insurance medical claims between 2000 and 2007. The study s...

testicular cancer is one of the commonest cancers in men of working age, and is increasing in incidence in europe and north america. one suggested mechanism of causation is that there is impaired differentiation of germ cells in the pre- or perinatal period, followed by malignant transformation in later life, possibly by a hormonal mechanism. endocrine disrupting chemicals (edcs) have been a ma...

We report a case that an ileo-ileal fistula in the pelvis due to Crohn's disease adhered rectum, formed abscess, and resulted multiple nodular protrusion rectum resembling phlegmonous colitis. In disease, inflammation of ileum may spread form cystic or rectal fistulas. It was considered rare endoscopic finding could be seen disease.

Neuroendocrine dysplasia in the large intestine is a rare disease entity that mostly encountered in association with inflam-matory bowel disease, especially ulcerative colitis. 1 Neuroendo-crine dysplasia is defined primarily by the size of the neuroendo-crine cell nests, and differs from neuroendocrine hyperplasia or microcarcinoid tumors. One hypothesis of developing neuroendocrine dysplasia ...

Chronic diarrhea is a symptom which persists for ≥ 4 weeks as of disease. often becomes the patient’s cause to be referred gastroenterology. In general, prevalence chronic approximated 5% in each populations, but there are obstacles diagnosing diarrhea, due many differential diagnoses diarrhea. The could neoplasm and non-neoplasm. several studies, through results colonoscopy histopathology, it ...

The purpose of this study was to investigate the consistency of rectal sparing using multiple periodic quality assurance computerized tomography imaging scans (QACT) obtained during the course of proton therapy for patients with prostate cancer treated with a hydrogel spacer. Forty-one low- and intermediate-risk prostate cancer patients treated with image-guided proton therapy with rectal space...

Osteoblastoma is an unusual neoplasm, usually found in the vertebral column and long bones of extremities. Maxillary involvement extremely rare. We present a case report benign osteoblastoma maxilla affecting 17 year old young male patient. The clinical presentation, radiological histopathological features as well treatment modalities this neoplasm are briefly discussed. Lastly attempt made to ...