PURPOSE To determine whether large rectal volume on planning computed tomography (CT) results in lower tumor regression grade (TRG) after neoadjuvant concurrent chemoradiotherapy (CCRT) in rectal cancer patients. MATERIALS AND METHODS We reviewed medical records of 113 patients treated with surgery following neoadjuvant CCRT for rectal cancer between January and December 2012. Rectal volume w...

Introduction: Colorectal cancer is ranked third among the most commonly diagnosed malignancies and second leading causes of death in world. However, only a few case reports are found literature regarding skin metastases originating from rectal cancer, which usually shows widespread disease poor prognosis.

BACKGROUND/AIMS The aim of this study was to evaluate the accuracy of 3-T magnetic resonance imaging (MRI) in locating rectal cancer, and to determine whether tumor location correlates with the incidence of pulmonary metastasis. MATERIALS AND METHODS A total of 146 patients with confirmed rectal adenocarcinoma underwent 3-T rectal MRI, and abdominal and chest computed tomography (CT) within 2...

Neoadjuvant radio-chemotherapy followed by total mesorectal excision (TME) is the standard treatment option for stage II and III rectal cancer. However, for pT3N0 rectal cancer patients who receive upfront TME, the lack of an efficient method to predict their prognosis hampers postoperative treatment. A low lymphocyte-to-monocyte ratio (LMR) is associated with an unfavorable prognosis for certa...

Cigarette smoking has been identified as a risk factor for colon cancer, however, much less is known about the association between cigarette smoking and rectal cancer. The purpose of this article is to evaluate the associations between rectal cancer and active and passive cigarette smoking and other forms of tobacco use. We also evaluate how genetic variants of GSTM-1 and NAT2 alter these assoc...

BACKGROUND Associations between selenium and cancer have directed attention to role of selenoproteins in the carcinogenic process. METHODS We used data from two population-based case-control studies of colon (n = 1555 cases, 1956 controls) and rectal (n = 754 cases, 959 controls) cancer. We evaluated the association between genetic variation in TXNRD1, TXNRD2, TXNRD3, C11orf31 (SelH), SelW, S...

nodes even in the same category of T3 cancer in patients without radiation therapy. The distal resection margin (DRM) means the length of the tumor-free normal mucosa and rectal wall. Han et al. [3] published the manuscript, ‘Association between a close distal resection margin and recurrence after sphincter-saving resections for T3 midor low-rectal cancer without radiotherapy.’ With retrospecti...

High-resolution rectal MRI plays a crucial role in evaluating rectal cancer by providing multiple prognostic findings and imaging features that guide proper patient management. Quality reporting is critical for accurate effective communication of the information among multiple disciplines, for which a systematic structured approach is beneficial. Existing guides on reporting of rectal MRI are d...

Background. Here we present a concise review on the evaluation and management of locally recurrent rectal cancer, which despite marked reductions in the rate of recurrent rectal cancer remains an important problem. Methods. This educational review discusses the diagnosis, evaluation, and management of recurrent rectal cancer. Results. Despite improvements in both the neoadjuvant and surgical ma...

Standard treatment for stage II and III rectal cancer has long consisted of neoadjuvant long-course chemoradiotherapy (CRT) or short-course radiotherapy (SCRT) followed by total mesorectal excision...