Fragrant species of the genus Salvia have been attributed many medicinal properties, which include anticancer activity. In the present study, cytotoxic properties of total methanol extract of Salvia chloroleuca Rech. f. & Aellen and its fractions were investigated on MCF- 7, a breast carcinoma cell line. Malignant and non-malignant cells were cultured in RPMI medium and incubated with different...

The biological activity and composition of the essential oil of Sclerorhachis leptoclada Rech. f. an endemic species from northeast of Iran was studied. The essential oil was isolated from the aerial flowering parts of the plant and analyzed by GC and GC-MS. Fifty-four compounds accounting for 95.9% of the total oil were characterized. The main constituents were (E)-nerolidol (14.5%), terpinen-...

The cytotoxic chloroform fraction of Euphorbia aellenii afforded two cycloartane type triterpenes — cycloart-25-en-3,24-diol (1) and 24-methylene-cycloartan-3-ol (2) — for the first time from this plant. Preparation of cycloartane derivatives, 3, 24-O-diacetyl-cycloart-25-en as compound 3 and 3-O-acetyl-24-methylene-cycloartan (4) were conducted by acetylating of 1 and 2, respectively. The ...

In models of Escherichia coli recombination and DNA repair, the RuvABC complex directs the branch migration and resolution of Holliday junction DNA. To probe the validity of the E. coli paradigm, we examined the impact of mutations in DeltaruvAB and DeltarecU (a ruvC functional analog) on DNA repair. Under standard transformation conditions we failed to construct DeltaruvAB DeltarecG, DeltarecU...

BACKGROUND Mindium laevigatum (Vent.) Rech. F. plant grows in central part of Iran. And used by local people as medical plant. OBJECTIVES The purpose of this study was to investigate the in vitro antibacterial, antifungal and antioxidant activities of the methanolic extracts of aerial and flower parts of plant. MATERIALS AND METHODS The leaves and stem and flower of bark from M. laevigatum ...

in the present study, an oxidative conversion of non-fluorescent dichlorofluoroscein (ldcf) to fluorescent dichlorofluoroscein (dcf) was used for detection of antioxidant properties of plant extracts. the rate of the reaction was followed by monitoring the formation of dcf as a function of time. the antioxidant assay was carried out for different concentrations of gallic acid, salvia mirzayanii...