OBJECTIVE To describe tardive rebound anxiety phenomena (panic, anxiety and insomnia) following abrupt paroxetine discontinuation. METHOD Case report, with comprehensive literature review on rebound and withdrawal phenomena associated with psychotropic medications. RESULTS Three different discontinuation syndromes with psychotropics are described: (1) new-onset CNS-depressant type withdrawa...

Sandwich-cultured human hepatocytes (SCHH) have been widely used for in vitro assessments of biliary clearance. However, the modulation of metabolism enzymes has not been fully evaluated in this system. The present study was therefore undertaken to determine the activity of cytochrome P450 (P450) 1A2, 2C8, 2C9, 2C19, 2D6, and 3A and to evaluate the impact of 1-aminobenzotriazole (ABT) on hepati...

The role of neutralizing antibodies (NAbs) during virus rebound in human immunodeficiency virus type 1 (HIV-1)-infected patients undergoing highly active antiretroviral therapy is poorly understood. Three patients in this study had NAbs to preexisting autologous HIV-1 and an episode of virus rebound after a prolonged period of virus suppression. To investigate the influence of NAbs on virus evo...

A retrospective study was conducted to assess the effects of various degrees of virologic rebound on CD4 cell counts over time in human immunodeficiency virus-infected patients. We found that (1) the higher the degree of virologic rebound, the more rapid the decrease in CD4 cell counts over time, and (2) the magnitude of the virologic rebound was inversely correlated with the CD4 cell counts at...

This article sketches the problem of indirect energy use effects, also known as rebound, of energy conservation. There is widespread support for energy conservation, especially when it is voluntary, as this seems a cheap way to realize environmental and energy-climate goals. However, this overlooks the phenomenon of rebound. The topic of energy rebound has mainly attracted attention from energy...

Background: The adiposity rebound is the second rise in body mass index that occurs between 3 and 7 years. An early age at adiposity rebound is known to be a risk factor for later obesity. The aim here is to clarify the connection between the age at rebound and the corresponding pattern of body mass index change, in centile terms, so as to better understand its ability to predict later fatness....

BACKGROUND Modeling childhood body mass index (BMI) trajectories, versus estimating change in BMI between specific ages, may improve prediction of later body-size-related outcomes. Prior studies of BMI trajectories are limited by restricted age periods and insufficient use of trajectory information. METHODS Among 3,289 children seen at 81,550 pediatric well-child visits from infancy to 18 yea...

BACKGROUND AND OBJECTIVES There are few data evaluating the role of inpatient rebound bilirubin levels in the management of infants readmitted after their birth hospitalization for indirect hyperbilirubinemia. The goal of the present study was to evaluate the clinical utility of inpatient rebound bilirubin levels within this patient population. METHODS A retrospective cohort study was conduct...

We analyze the internal permutations of Keccak, one of the NIST SHA-3 competition finalists, in regard to differential properties. By carefully studying the elements composing those permutations, we are able to derive most of the best known differential paths for up to 5 rounds. We use these differential paths in a rebound attack setting and adapt this powerful freedom degrees utilization in or...

Accurate measurement of intra-ocular pressure is a fundamental component of the ocular examination. The most common method of measuring IOP is by Goldmann applanation tonometry, the accuracy of which is influenced by the thickness and biomechanical properties of the cornea. Algorithms devised to correct for corneal thickness to estimate IOP oversimplify the effects of corneal biomechanics. The ...