An immunohistochemical study of reactive pleural lesions, adenocarcinomas and mesotheliomas using carcinoembryonic antigen (CEA), cytokeratin and vimentin was carried out. All the specimens were obtained at surgery except for 11 mesotheliomas found at necropsy. Vimentin was positive in 23 of 27 mesotheliomas and negative in all the adenocarcinomas and 4 of 17 reactive mesothelial lesions. Conve...

Pulmonary nodular lymphoid hyperplasia (PNLH) is a reactive lymphoid proliferation manifesting as multiple solitary nodules or localized infiltrates in the lungs. It is a type of benign lymphoproliferative disease that can affect the lungs. We present the case of a 41-year-old female patient with respiratory symptoms such as productive cough, left chest pain, and dyspnea. Imaging findings revea...

Correspondence: Dr Abhimanyu Jha, MBBS, MD Associate Professor, Department of Pathology Maharajgunj Medical Campus, TU, IOM, Kathmandu, Nepal Email: [email protected]. Background: Diseases of the cervix are common in women. Detection of neoplastic lesions is of prime importance in the evaluation of cervical smears although their frequency is less than the non-neoplastic conditions. Reactiv...

Abstract Background. Langerhans cell histiocytosis is a rare reactive proliferative disorder marked by excess proliferation and accumulation of mononuclear phagocytes in tissues organs. Usually, organs systems where cells are normally found involved. Lesions may be limited to one system single- or multisite, many The etiology not fully known. According the hypotheses, immune dysfunction due exu...

Physiological processes, as aerobic metabolism and inflammatory response, generate reactive oxygen species (ROS) that may induce cellular injury when their amount is increased and antioxidant defense mechanisms are overwhelmed. Also, ROS are generated following UV skin irradiation able to deplete the natural antioxidant defenses in the skin. The increase in exposure to UV may lead to photoaging...

Since heart lesions occur in many patients with rheumatoid arthritis (RA), sera from these patients were tested with an indirect fluorescent technique for antibodies reactive with rat heart cell cultures. Of 27 sera 22 had reactivity with non-muscle (nM) cells and 3 reacted with cultured beating muscle cells (M). Positive sera reactive with nM cells exerted complement-dependent cell cytotoxicit...

The oral cavity can be affected by a wide variety of disorders characterized by inflammation of the gingiva and/or oral mucosa. In dogs and cats, differential diagnoses for generalized oral inflammatory disorders include plaque-reactive mucositis, chronic gingivostomatitis, eosinophilic granuloma complex, pemphigus and pemphigoid disorders, erythema multiforme, and systemic lupus erythematosus....

The clinical forms of leprosy constitute a spectrum that correlates closely with the degree of cell-mediated immunity. Patients with tuberculoid leprosy develop strong cell-mediated responses and have only a few, localized lesions, whereas patients with multibacillary lepromatous leprosy are specifically unresponsive to antigens of Myobacterium leprae. T cells of the CD4+ subset predominate in ...

Reactive arthritis is associated with demonstrable infection at a distant site without evidence of sepsis at the affected joint(s). We present a rare case reactive arthritis where no bacterial or chlamydial infections could be established, rather larvae of Strongyloides stercoralis could be demonstrated in the stool and duodenal biopsy. Reactive arthritis, psoriasiform lesions and malabsorption...

We report a case of Hodgkin lymphoma (classic type) referred for response assessment after two cycles of chemotherapy with ABVD regiment. The F-18 fluorodeoxyglucose positron emission tomography (F-18 FDG PET/CT) showed hypermetabolic cutaneous and subcutaneous lesions with a linear pattern in the left arm with significant F-18 fluorodeoxyglucose positron accumulation in associate with left axi...