Let T = (T∗, T△) be a spherical latin bitrade. With each a = (a1, a2, a3) ∈ T ∗ associate a set of linear equations Eq (T, a) of the form b1 + b2 = b3, where b = (b1, b2, b3) runs through T ∗ \ {a}. Assume a1 = 0 = a2 and a3 = 1. Then Eq (T, a) has in rational numbers a unique solution bi = b̄i. Suppose that b̄i 6= c̄i for all b, c ∈ T ∗ such that Supported by grant MSM 0021620839 Supported by Edu...

We use first-principles density-functional theory calculations to investigate the dependence of tetragonality on local structure in a variety of ferroelectric solid solutions. We demonstrate that tetragonality is strongly coupled to the B-cation displacement and weakly coupled to the A-cation displacement. Examination of various BiMO3 additives to PbTiO3 for different M 3+ ionic sizes reveals t...

Significant mechanical stability is an essential feature shared by many elastomeric proteins, which function as molecular springs in a wide variety of biological machinery and biomaterials of superb mechanical properties. Despite the progress in understanding molecular determinants of mechanical stability, it remains challenging to rationally enhance the mechanical stability of proteins. Using ...

In recent years, several molecularly targeted therapies have been approved for clear cell renal cell carcinoma (ccRCC), a highly aggressive cancer. Although these therapies significantly extend overall survival, nearly all patients with advanced ccRCC eventually succumb to the disease. To identify other molecular targets, we profiled gene expression in 90 ccRCC patient specimens for which tumor...

Protein N-terminal acetyltransferase D (NatD, NAA40) that specifically acetylates the alpha-N-terminus of histone H4 and H2A has been implicated in various diseases, but no inhibitor reported for this important enzyme. Based on acetyl transfer mechanism NatD, we designed prepared a series highly potent NatD bisubstrate inhibitors by covalently linking coenzyme A to different peptide substrates ...

This paper presents the Malmö Breast Tomosynthesis project. The tomosynthesis equipment is described as well as the patient selection and image acquisition. Special focus is given to one of the studies of the project, which is a comparison of the diagnostic performance between breast tomosynthesis (BT), digital mammography (DM) and ultrasonography (US): Tumor classification according to the BIR...

Focusing on the working relationship between Marketing Managers and Sales Managers, our study examines two dimensions of interpersonal conflict: dysfunctional conflict and functional conflict. Drawing on relevant theory, we include three communication variables – frequency, bidirectionality, and quality – as antecedents in our structural model. Using these explanatory variables we predict the t...

We propose to model breast tissue in mammograms covering both density and tissue patterns. The breast tissue density modelling is based on the global density distribution of the breast region. We segment the whole breast region into a number of uniform density sub-regions and construct an overall density model of the breast using the relative proportions of these sub-regions. The breast tissue ...

Abstract Traditional triethylamine (TEA) sensors suffer from the drawback of serious cross-sensitivity due to low charge-transfer ability gas-sensing materials. Herein, an advanced anti-interference TEA sensor is designed by utilizing interfacial energy barriers hierarchical Bi 2 O 3 /WO composite. Benefiting abundant slit-like pores, desirable defect features, and amplification effect heteroju...