UNLABELLED In patients with myocardial infarction (MI), an expansion of the remote normal regions of the left ventricle is often observed. However, the characteristics of such regions are not fully understood. Thus, we investigated this issue from the standpoint of myocardial oxidative metabolism using (11)C-acetate PET. METHODS In 33 patients with recent MI (24 not receiving beta-blockers, 9...

BACKGROUND AND OBJECTIVES To compare the effect of dexmedetomidine and fentanyl on hemodynamic changes in chronic male smokers. METHODS This is a prospective, randomized, blinded study. Were selected 60 chronic male smokers (aged 16 to 60 years). The patients were randomly divided into two groups: Group D (n=30) received 1μg.kg(-1) dexmedetomidine and Group F (n=30) received 3μg.kg(-1) fentan...

The haemodynamic effects of large bolus doses of metocurine 0.45 mg kg-1 and pancuronium 0.1 mg kg-1 were compared in patients with coronary artery disease anaesthetized with diazepam, anileridine and nitrous oxide. Hypotension occurred more frequently after metocurine and was a result of a decrease in systemic vascular resistance. After pancuronium there was no increase in arterial pressure or...

patients and methods in a double-blind clinical trial, 103 patients (american society of anesthesiologists class i, ii) aged 18 - 45 years old, who were septorhinoplasty candidates, were randomly assigned into two groups, a 900 mg gabapentin group and placebo, in amir-al-momenin academic hospital. the drug was prescribed to the patients orally, 2 hours before the operation. anesthetic technique...

objective: rosa damascena mill l. (r. damascena) is a well-known plant with fragrant effects. several therapeutic effects of this plant on respiratory, gastrointestinal and nervous systems have been reported. it is also suggested to have beneficial effect on cardiovascular system especially blood pressure regulation. the present study was carried out to evaluate acute cardiovascular effect of h...

objective(s) calcium-channel blockers have an important role in the treatment of several cardiovascular disorders. derivatives of 1, 4-dihydropyridine are one of the most potent calcium antagonists. in this study four novel ', 4-dihydropyridine calcium channel blockers were synthesized and their hypotensive properties were investigated in male rats. materials and methods four 1, 4-dihydrop...

background: hand grip strength (hgs) is a reliable indicator of peripheral muscle strength. although, numerous studies have investigated the strength of hand grip; little attention has been given to coronary artery disease (cad) patients, exploring the relationship between hgs and myocardial oxygen consumption (mvo2) index. the current study aimed to evaluate the interaction between hgs and mvo...

BACKGROUND Properly titrated opiates decrease respiratory rate but do not affect tidal volume or induce respiratory acidosis. OBJECTIVE To determine whether remifentanil improves breathing pattern or reduces inspiratory effort in patients with acute respiratory failure and tachypnea or rapid shallow breathing. METHODS We studied 14 patients who developed tachypnea and/or rapid shallow breat...

background and objective: lactic acid is widely used in the food, chemical and pharmaceutical industries. the major problems associated with lactic acid production are substrate and end-product inhibition, and by-product formation. membrane technology represents one of the most effective processes for lactic acid production. the aim of this work is to increase cell density and lactic acid produ...

The purposes of this study were to evaluate the gender difference in exercise tolerance. We analyzed the relationship between the double product (DP) at the double product break-point (DPBP) and the systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), pulse pressure (PP), heart rate (HR) at DPBP. The subjects were 18 healthy men and 15 healthy women. Exercis...