نتایج جستجو برای: rapid biosynthesis
تعداد نتایج: 374759 فیلتر نتایج به سال:
The present investigation characterizes calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis in the rat. Intraperitoneal injection of A-23187 (20 mug/rat) stimulated marked biosynthesis of 6-keto-PGF(1alpha) (6-KPA), TxB(2), LTC(4) and LTB(4), with no detectable changes on levels of PGE(2). Levels of all eicosanoids decreased rapidly after a peak which was seen as early as 5 m...
Although cancer cells are frequently faced with a nutrient- and oxygen-poor microenvironment, elevated hexosamine-biosynthesis pathway (HBP) activity protein O-GlcNAcylation (a nutrient sensor) contribute to rapid growth of tumor emerging hallmarks cancer. Inhibiting could be promising anticancer strategy. The gluconeogenic enzyme phosphoenolpyruvate carboxykinase 1 (PCK1) is downregulated in h...
Tropane alkaloids such as scopolamine (C17H21NO4), atropine (C17H23NO3) and hyoscyamine (C17H23NO3) are the most important plant secondary metabolites in the pharmaceutical industry due to anticholinergic activity, competition with muscarinic receptors and also treating different human diseases. Scopolamine, hyoscyamine and atropine are the most important tropane alkaloids used as anticoagulant...
Based on recent statistical survey, the cancer is the third important factor in Iran mortality. Vinblastine and vincristine alkaloids are dominantly biosynthesized in the aerial parts of periwinkle, broadly applied for cancer treatment. Therefore, over production of these alkaloids by using the biotechnological approaches is inevitable. Since the terpenoid indole alkaloids (TIAS) biosynthesis p...
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