نتایج جستجو برای: randomized trial

تعداد نتایج: 441146  

Objective: This study aimed to compare the efficacy of rescue blankets with conventional blankets in terms of preventing hypothermia in the pre-hospital setting. Methods: In this randomized clinical trial, patients older than 18 years old with Cold Discomfort Scale (CDS) > 2, and those who were transferred to the emergency department (ED) by emergency medical service entered the study. Patients...

2008
Allan Abbass

This study evaluated the efficacy and long-term effectiveness of intensive short-term dynamic psychotherapy (ISTDP) in the treatment of patients with DSM-IV personality disorders (PD). Twenty-seven patients with PD were randomized to treatment with ISTDP or a minimal-contact, delayed-treatment control condition. ISTDP-treated patients improved significantly more than controls on all primary out...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2006
Robert Gray Judith Manola Scott Saxman John Wright Jan Dutcher Michael Atkins Michael Carducci William See Christopher Sweeney Glenn Liu Mark Stein Robert Dreicer George Wilding Robert S DiPaola

Given the increase in novel agents and difficulty with planning and completing many phase III studies, various phase II trial design options should be considered to more effectively guide phase III trial plans. The need for novel phase II trial designs has increased, given the number of novel molecular targeted therapies now available for testing, an abundance of cytostatic agents, and limited ...

2013
Sally Hopewell Gary S Collins Allison Hirst Shona Kirtley Abdelouahid Tajar Stephen Gerry Douglas G Altman

BACKGROUND For a randomized trial, the primary publication is usually the one which reports the results of the primary outcome and provides consolidated data from all study centers. Other aspects of a randomized trial's findings (that is, non-primary results) are often reported in subsequent publications. METHODS We carried out a cross-sectional review of the characteristics and type of infor...

2008
Jaffer A. Ajani Kathryn A. Winter

ANAL CANAL CARCINOMA IS AN uncommon malignancy in the United States. Among 1 437 180 new cancer diagnoses projected for the year 2008, approximately 5070 will be new cases of anal canal carcinoma. Anal canal carcinoma has a unique clinical biology that can be distinguished from all other gastrointestinal cancers. It is mostly a local-regional cancer, with a metastatic potential in only 15% of p...

2009
Pamela Lee Samantha Yim

Intervention: Randomly assigned conventional retraction or retraction with the wound-protection system. Patients were blinded to the study arm in which they were enrolled. All patients were given standardized preoperative antibiotics. Demographics including age, sex, body mass index, history of diabetes, and tobacco use were recorded. The severity of appendicitis as determined by the attending ...

2015
Alexander Brown Victor Alfieri Ayse Ozcan Edeer Valerie D. Olson

Objectives: To determine if a modified version of the cross body stretch that incorporates scapular stabilization immediately following a bout of pitching will increase passive shoulder range of motion more than the standard cross body stretch in male collegiate baseball players. Background: Overhead athletes, mainly baseball players, often exhibit pathologic gross internal rotation deficit (pG...

2007
Peter L. Elkin Dietlind Wahner-Roedler

Background: Concept-based Indexing is purported to provide more granular data representation for clinical records"'2 This implies that a detailed clinical terminology should be able to provide improved access to clinical records. To date there is no data to show that a clinical reference terminology is superior to a precoordinated terminology in its ability to provide access to the clinical rec...

2015
Anne Forster John Young Katie Chapman Jane Nixon Anita Patel Ivana Holloway Kirste Mellish Shamaila Anwar Rachel Breen Martin Knapp Jenni Murray Amanda Farrin

The high prevalence and diversity of longer-term problems experienced by patients with stroke and their carers has long been recognized, but they remain poorly addressed by existing services. Postdischarge contact with therapy services is associated with improved outcomes. However, these interventions are generally time limited and have little effect on psychosocial outcome. National guidelines...

2015
Vanessa Ieto

BACKGROUND: Snoring is extremely common in the general population and may indicate OSA. However, snoring is not objectively measured during polysomnography, and no standard treatment is available for primary snoring or when snoring is associated with mild forms of OSA. Th is study determined the eff ects of oropharyngeal exercises on snoring in minimally symptomatic patients with a primary comp...

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