The common view is that functional proteins or protein domains have unique and stable 3D structures characterized by the relatively fixed positions of their atoms and backbone Ramachandran angles that both vary slightly around their equilibrium positions due to low-amplitude thermal fluctuations. In addition there is another class of functional proteins and protein regions that contain smaller ...

We present 13 (3)J, seven (2)J and four (1)J coupling constants (24 in all) calculated using B3LYP/D95** as a function of the φ and ψ Ramachandran dihedral angles of the acetyl(Ala)(3)NH(2) capped trialanine peptide over the entire Ramachandran space. With the exception of three of these J couplings, all show significant dependence upon both dihedral angles. For each J coupling considered, a tw...

Background: MeICT is the first chlorotoxin-like peptide isolated from the Iranian Scorpion Mesobuthus eupeus. Chlorotoxin (CTX) is a neurotoxin that specially binds to (MMP-2) on ma-lignant cells and now is used in treatment of glioma. In the present study, we have used homology modeling to propose the 3D structure of MeICTand analyze its interaction with MMP-2 and its SNP types. Methods:The ...

We demonstrate the applicability of the polynomial degree bound technique to notions such as the nonexistence of Turing-hard sets in some relativized world, (non)uniform gap-definability, and relativized separations. This way, we settle certain open questions of Hemaspaandra, Ramachandran & Zimand [HRZ95] and Fenner, Fortnow & Kurtz [FFK94], extend results of Hemaspaandra, Jain & Vereshchagin [...

Jun Z. Li, Devin M. Absher, Hua Tang, Audrey M. Southwick, Amanda M. Casto, Sohini Ramachandran, Howard M. Cann, Gregory S. Barsh, Marcus Feldman,* Luigi L. Cavalli-Sforza,* Richard M. Myers* *To whom correspondence should be addressed. E-mail: [email protected] (M.F.); [email protected] (L.L.C.S.); [email protected] (R.M.M.) Published 22 February 2008, Science 319, 1100 (2008)...

s from the First International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2012) Chennai, India. 20-22 January 2012 Edited by Suniti Solomon, Sunil S Solomon, Pachamuthu Balakrishnan, Kailapuri G Murugavel, Shanmugam Saravanan, Hussain S Iqbal and Ramachandran Vignesh Published: 4 May 2012 These abstracts are available online at http://www.biomedcentral.com/bmcinfectdis/supple...

Psychicones: Visual Traces of the Soul in Late Nineteenth-Century Fluidic Photography Nicolas Pethes 325 ‘It’s All Done With Mirrors’: V.S. Ramachandran and the Material Culture of Phantom Limb Research Katja Guenther 342 Drawing as Instrument, Drawings as Evidence: Capturing Mental Processes with Pencil and Paper Alicia Puglionesi 359 Brain Ways: Meynert, Bachelard and the Material Imagination...

In [Dhandapani and Ramachandran, “Area and power efficient DCT architecture for image compression”, EURASIP Journal on Advances in Signal Processing 2014, 2014:180] the authors claim to have introduced an approximation for the discrete cosine transform capable of outperforming several well-known approximations in literature in terms of additive complexity. We could not verify the above results ...

If two neutral density (ND) filters overlap partially, the luminance of the overlapping region is given by a multiplicative relationship (e.g., if the filters have 50% transmittance then on a 100 cd m-2 background, the luminance of each filter would be 50 cd m-2 but the luminance of the overlapping region would be 50% of 50 cd m-2, i.e. 25 cd m-2). Does the visual system respect this relationsh...