The insertion into an animal tumor of buried capillary glass tubes containing radium emanation presents a comparatively new departure in radium therapy and is undoubtedly destined to play a prominent part in the future development of the whole field of radiotherapeutics. The technique employed on animals and human beings is as follows: Radium emanation, the first active product of decomposition...

The radium atom is a promising system for studying parity and time invariance violating weak interactions. However, available experimental spectroscopic data for radium is insufficient for designing an optimal experimental setup. We calculate the energy levels and transition amplitudes for radium states of significant interest. Forty states corresponding to all possible configurations consistin...

This little book gives a short account of cases treated by the author with radium in the hope that it may draw the attention of the general practitioner and student to the conditions in which this valuable therapeutic agent may be of use. The first portion of the work is devoted to a short summary of the physical problems connected with radium, including apparatus, screening, methods of applica...

Very little is known concerning the changes that occur in living tissue following the injection of solutions of an “active deposit’’ of radium emanation. This investigation was undertaken to determine what changes occur in the principal organs of the animal body following such a treatment, and to afford data that might act as a guide in the treatment of certain types of cancer, in which the sol...

In 2004, docetaxel was approved for the treatment of metastatic castration-resistant prostate cancer (mCRPC). For the next several years, there was a lull in drug approvals. However, from 2010 onwards, 5 additional therapies have been approved on the basis of showing a survival benefit in phase III studies. These agents include sipuleucel-T, cabazitaxel, abiraterone, enzalutamide and (most rece...

Prostate cancer is the most common malignant disease in men. Several therapeutic agents have been approved during the last 10 years. Among them, radium-223 dichloride (Xofigo®) is a radioactive isotope that induces irreversible DNA double-strand breaks and consequently tumor cell death. Radium-223 dichloride is a calcium-mimetic agent that specifically targets bone lesions. Radium-223 dichlorid...

Background: Measurement of the radiation dose distribution is important in assessing the health risk a population and serve as reference in documenting changes to environmental radioactivity in soil due to man-made activities. Materials and Methods: The activity concentration of 238U, 232Th and 40K in soil samples obtained from different locations in Ajaokuta Local Government area was measured ...

manner that a medical practitioner will have not only no difficulty in following the author, but also will positively enjoy reading him. The author first of all deals with the physics of radium: next the apparatus and means of application, then the sensitivity of the tissues to radium, and. proceeds to deal with malignant growths in various situations, which are suitable for radium therapy. The...

The discovery of radium by Madame Curie in 1898 opened up a field of physical research the limits of which it is impossible to see. Although it was found at an early stage that radium had a definite action upon living tissues, this appeared to be purely destructive, and it is only recently that the selective action of radium upon cancer cells has been adequately demonstrated. Depending as it do...