Electrochemotherapy uses electroporation for enhancing chemotherapy. Electrochemotherapy can be performed using standard operating procedures with predefined electrode geometries, or using patient-specific treatment planning to predict electroporation. The latter relies on realistic computer models to provide optimal results (i.e. electric field distribution as well as electrodes' position and ...

BACKGROUND Identifying those patients who have a higher chance to be cured with fewer side effects by particle beam therapy than by state-of-the-art photon therapy is essential to guarantee a fair and sufficient access to specialized radiotherapy. The individualized identification requires initiatives by particle as well as non-particle radiotherapy centers to form networks, to establish proced...

Developments in radiotherapy during the past 10– 15 years, which have been driven largely by technological advances, have been nothing short of remarkable. Significant advances in tumour imaging, in radiotherapy treatment planning, and in dose delivery techniques have all contributed to improved treatment outcomes and have, in some situations, led to important changes in overall therapeutic app...

objectives: the aim of this study was to verify the treatment planning systems (tpss). the next aim was to validate imsure qa software for patient-specific qa in radiotherapy clinics.  material and methods: we used imsure qa software (standard imaging, v 3.5) for verification of 92 non-imrt plans (540 fields) in 10 radiotherapy clinics. to validate the imsure, dose measurement was performed in ...

INTRODUCTION There is limited evidence to guide the preparation of patients for radiotherapy. This paper describes the protocol for an evaluation of a radiation therapist led education intervention delivered to patients with breast cancer in order to reduce psychological distress. METHODS A multiple-baseline study is being used. Usual care data is being collected prior to the start of the int...

Four-dimensional (4D) radiotherapy is the explicit inclusion of the temporal changes in anatomy during the imaging, planning, and delivery of radiotherapy. Temporal anatomic changes can occur for many reasons, though the focus of the current investigation is respiration motion for lung tumors. The aim of this study was to develop 4D radiotherapy treatment-planning methodology for DMLC-based res...

BACKGROUND High grade gliomas (HGG) are typically treated with a combination of surgery, radiotherapy and chemotherapy. Three dimensional (3D) conformal radiotherapy treatment planning is still the main stay of treatment for these patients. New treatment planning methods suggest better dose distributions and organ sparing but their clinical benefit is unclear. The purpose of the current study w...

Introduction: Radiotherapy (RT) plays a major role in the management of breast cancer. Cardiac Toxicity is an important late complication of radiotherapy for left sided Breast cancer. Cardiac morbidity can be minimized through careful treatment planning. Aim: To study the variation of dose to the heart by change in the depth of normalization point during Radiotherapy planning. Settings and desi...

Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, is a rare form of non-Hodgkin lymphoma. Treatment of ENKTL primarily relies on radiation; thus, proper delineation of target volumes is critical. Currently, the ideal modalities for delineation of gross tumor volume for ENKTL are unknown. We describe three consecutive cases of localized ENKTL that presented to the Nova Scotia Cancer...

Modern advances in computers have fueled parallel advances in imaging technologies. The improvements in imaging have in turn allowed a higher level of complexity to be incorporated into radiotherapy treatment planning systems. As a result of these changes, the delivery of radiotherapy evolved from therapy designed based primarily on plain (two dimensional) x-ray images and hand calculations to ...