BACKGROUND ERCP practically requires moderate to deep sedation controlled by a combination of benzodiazepine and opiod. Propofol as a sole agent may cause oversedation. A combination (cocktail) of infused propofol, meperidine, and midazolam can reduce the dosage of propofol and we hypothesized that it might decrease the risk of oversedation. We prospectively compare the efficacy, recovery time,...

CytochromeP450 (P450) and uridine 59-diphospho-glucuronosyltransferase (UGT) are major metabolizing enzymes in the biotransformation of most drugs. Altered P450 and UGT activities are a potential cause of adverse drug-drug interaction. A method for the simultaneous evaluation of the activities of five P450s (CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A) and four UGTs (UGT1A1, UGT1A4, UGT1A9, and ...

A Radiopharmaceutical is a radioactive compound used for the diagnosis and treatment of human diseases. Radiopharmaceuticals are among the most highly regulated materials administered to patients because they are controlled both as drugs and as radioactive substances. The use of radiopharmaceuticals for any purpose is governed by regulatory agencies in different countries all over the wor...

Our previous studies indicated that a cocktail of pyrazine analogs, identified in wolf urine, induced avoidance and fear behaviors in mice. The effects of the pyrazine cocktail on Hokkaido deer (Cervus nippon yesoensis) were investigated in field bioassays at a deer park in Hokkaido, Japan. A set of feeding bioassay trials tested the effects of the pyrazine cocktail odor on the behavior of the ...

Vitamin B Cocktail A daily vitamin B cocktail (vitamin B6, vitamin B12 and folic acid) is among the most important supplements that an afibber, or anyone else for that matter, can take. The vitamin B cocktail effectively lowers the level of homocysteine in the blood. High levels of homocysteine, a sulfurcontaining amino acid, is associated with an increased risk of stroke and is also involved i...

After observing an increased incidence of imprecise and sometimes erroneous use of nuclear chemistry, radiochemistry, and radiopharmacy related terms and nomenclature in scientific reports, an international working group of experts was assembled to address the issue. Upon extensive consultation with peers within the field of radiochemistry and radiopharmaceutical sciences over a 3-year period a...

Department Radiopharmaceutical and Radiopharmaceutical Cancer Research, H 01328 Dresden, Germany. E-mail: t.kn +493512602760; +493512602622 Department of Chemistry and Food Che 01062 Dresden, Germany Department of Oncology, Cross Cancer In Alberta, Canada T6G 1Z2 Centre for Translational Bone, Joint, and S University Hospital, Technische Universität, Department of Inorganic Solid State Chemi Ro...