UNLABELLED Terbium offers 4 clinically interesting radioisotopes with complementary physical decay characteristics: (149)Tb, (152)Tb, (155)Tb, and (161)Tb. The identical chemical characteristics of these radioisotopes allow the preparation of radiopharmaceuticals with identical pharmacokinetics useful for PET ((152)Tb) and SPECT diagnosis ((155)Tb) and for α- ((149)Tb) and β(-)-particle ((161)T...

investigators have studied this problem. The autopsy studies of Custer2’3 and Hashimoto4 are directed largely toward efforts to establish the size of the “normal” marrow organ. Shillingford,5 in autopsy studies of patients in heart failure, demonstrated grossly visible expansion of red marrow in long bones. Kramer and Wynne6 made external counts of radioactivity along the extremities after trac...

The principles and scope of the application of radioisotopes and ionising radiation in industry are reviewed as an introduction to nuclear methods of control in sugar milling and refining. Details of the South African usage of radioactive materials are given, indicating the absence of the sugar industry. The potential of the radiotracer technique is emphasised in the light of reported investiga...

—Microsatellite multiplexing is a powerful technique that can increase the productivity of genetic studies in fisheries biology. We review multiplexing methods and present an optimized and detailed protocol for microsatellite multiplexing that is specifically tailored for use with radioisotopes. The protocol can significantly reduce the cost associated with microsatellites and provides high pol...

than that used by American investigators. Exploration with other pure Beta emitters in colloidal form is in progress. Investigations in the intracavitary injections of liquid radioisotope such as sodium, bromine, and colloidal gold, or interstitial implantation of tantalum wire or gold grain for the treatment of carcinoma of the urinary bladder is reported by the Royal Marsden Hospital group of...

Copper (Cu) is an important trace element in humans; it plays a role as a cofactor for numerous enzymes and other proteins crucial for respiration, iron transport, metabolism, cell growth, and hemostasis. Natural copper comprises two stable isotopes, (63)Cu and (65)Cu, and 5 principal radioisotopes for molecular imaging applications ((60)Cu, (61)Cu, (62)Cu, and (64)Cu) and in vivo targeted radi...

The research on diagnostic imaging agents is an area of bioiorganic chemistry which includes the design of ligands, the coordination reaction between the ligands and the radionuclide, radiochemical characterization and biodistribution studies. Over the past three decades, biospecific imaging agents have evolved from large molecules to small ones with biologic activity. The coordination of a rad...

By measuring the concentration of four xenon radioisotopes in the atmosphere, the International Monitoring System (IMS) can verify nuclear weapons tests around the world. To measure ultra-low concentrations of radioxenons, many detection systems, such as the Automated Radioxenon Sampler and Analyzer (ARSA) and the Swedish Automatic Unit for Noble gas Acquisition (SAUNA), have been developed and...

Based on general arguments presented in this report, nuclear criticality was eliminated from performance assessment calculations for the Waste Isolation Pilot Plant (WIPP), a repository for waste contaminated with transuranic (TRU) radioisotopes, located in southeastern New Mexico. At the WIPP, the probability of criticality within the repository is low because mechanisms to concentrate the fis...