Malignant melanoma of the vagina, a very rare malignancy, has a notoriously aggressive behavior associated with a high risk of local recurrence and distant metastasis. At present, there are various treatment options for this disease but no standard guideline. We describe a case of a 54-year-old woman with a locally advanced melanoma of the vagina, who underwent radical surgery, biochemotherapy ...

We present a case of scalp reconstruction using Integra and split skin grafting after extensive excision of melanoma in a previously irradiated field. Radical resection of malignancy and application of Integra, a dermal substitute, was performed. Following histological confirmation of complete excision, a split-thickness skin graft (SSG) was applied. After 14 months the patient remains fully he...

The incidence of breast cancer complicating chronic mastitis with epitheliosis has been reported to be as high as 45% and as low as 6%. At least part of this discrepancy appears to be due to difficulty in distinguishing between benign and malignant intraduct epithelial proliferation.A small series is presented here in which the incidence of invasive cancer after local excision of breast tissue ...

Clinicopathologic correlation of five cases of cystadenomas of the liver are reported. All patients were female and radical surgical procedure, total excision or resection was performed four times, and partial excision once. In all patients the postoperative course was uneventful and they are all alive and well. Examined by conventional histological and special immuno-histochemical stains the t...

Generally, the gold standard of radical surgery for gastrointestinal (GI) tumors is en bloc resection of primary lesions and their related tissues. For gastric cancer, the ideal surgical treatment should be D2 radical gastrectomy plus complete mesogastrium excision. Complete mesogastrium excision is rarely done or mentioned since little is known about the mesogastrium and its presence is still ...

OBJECTIVE To report a rare case of penile paraffinoma caused by the subcutaneous or intra-urethral injection of foreign substances containing long-chain saturated hydrocarbons. These were injected in order to increase the penis size which generated a chronic granulomatous inflammatory reaction. This is a rare practice in the western world. METHODS We present the case of a 32-year-old Bulgaria...

BACKGROUND: Leiomyosarcomas (LMS) of the spermatic cord are extremely rare. Radical inguinal orchiectomy and high ligation of the cord is the standard primary surgical procedure. The extent of surrounding soft tissue excision required and the precise role of adjuvant radiotherapy, however, remains unclear. In addition, recurrence is a commonly encountered problem which might necessitate further...

A young man presented with a perineal tumour which despite intensive investigation, remained of unknown origin and required radical excision. It was subsequently shown to be a metastasis from a primary regressed testicular teratoma. It is important to exclude a testicular origin in these patients wherever possible because such tumours are often chemosensitive.

Background: Carcinosarcoma of hypopharynx is a rare neoplasm with both malignant epithelial and mesenchymal components. They are highly aggressive in nature with controversial histogenesis. To our knowledge, there is no case reported of carcinosarcoma of hypopharynx managed with wide LASER excision and modified radical neck dissection followed by chemoradiation. Method and Result: 42-year-old m...

Chondrosarcoma is a malignant tumor in which the tumor cells produce cartilage but not bone. The recommended management is wide local or radical excision, followed by surgical and prosthetic reconstruction. This article explains postsurgical prosthetic rehabilitation of a chondrosarcoma patient by means of intraoral acrylic, and extraoral silicone prosthesis for restoration of normal orofacial ...