In responding to Drs. Calabrese and Baldwin’squestion, “At what point, if ever, should hormesis beemployed as the principal dose response default assump-tion in risk assessment? “, we examined the benefits ofreplacing traditional dose response with hormesis. Ingeneral, hormesis provides more complete usefulinformation for risk assessment than does traditionaldose-res...

Media reports of deaths and devastation produced by atomic bombs convinced people around the world that all ionizing radiation is harmful. This concentrated attention on fear of miniscule doses of radiation. Soon the linear no threshold (LNT) paradigm was converted into laws. Scientifically valid information about the health benefits from low dose irradiation was ignored. Here are studies which...

The objective of the present study was to evaluate periodical UV-B radiation hormesis during kale seeds germination in their main content secondary metabolite compounds (phenols; glucosinolates; total antioxidant capacity –TAC–) and changes a refrigerated shelf-life. doses received were 0, 5, 10, 15 kJ m−2 (CTRL, UVB5, UVB10, UVB15) where 25% applied on 3rd, 5th, 7th, 10th sprouting day. UV did...

Hormesis refers to the beneficial effects of a treatment that at a higher intensity is harmful. In one form of hormesis, sublethal exposure to stressors induces a response that results in stress resistance. The principle of stress-response hormesis is increasingly finding application in studies of aging, where hormetic increases in life span have been seen in several animal models.

How much radiation does it take to cause our risk for an observable health effect to increase? Is there a level of radiation that is safe? How is radiation beneficial? The question of an effect occurring because of radiation exposure and the question of whether low‐ level radiation is safe are much‐debated topics. There are many thoughts on the answers to these questions, and suggested answers ...

OBJECTIVE In this commentary I respond to points raised in the commentary by Mushak [Ad hoc and fast forward: the science and control of hormesis growth and development. Environ Health Perspect 117:1333-1338 (2009)], which principally concerns studies by me and my colleagues concerning the frequency of hormesis in toxicology. DISCUSSION In this commentary I demonstrate that Mushak's analysis ...

This study investigated 94.4% of Palestinian radio technologists and the mean percentage of correct answers for knowledge and awareness questions was 26.4%. The percentage of correct answers for questions testing knowledge of the ALARA (As Low As Reasonably Achievable) principle and hormesis hypothesis was 66.5% and 17.2%, respectively. Radio technologists with education level higher than bache...

This is a reflection from a certified health physicist regarding his becoming aware, during his 40-year career, that the linear no-threshold (LNT) model and the associated As Low As Reasonably Achievable concept have no scientific basis and make no positive contribution to radiation safety. They should be replaced by an alternative, scientifically based model that includes a threshold, below wh...

Perception of hormesis as a significant dose–response phenomenon is found in many sciences without predicting and/or quantifying this low-dose effect with statistical models. Only minority papers published on plant biology or other apply available modelling the relationships, along significance testing for and prediction sub-NOAEL quantities. The threshold quantities opens further evaluation op...

Dose-response curves for various low-LET radiation sources have consistently been demonstrated to be J-shaped for the cancer-relevant endpoint of neoplastic transformation in vitro. Most of these studies have been performed where the radiation has been delivered at intermediate to high dose-rates (30-3000 mGy/min), where the threshold dose for induction of neoplastic transformation is around 10...