BACKGROUND 1st generation 5-hydroxytryptamine receptor antagonists (5-HT3 RAs), and palonosetron, a 2nd generation 5-HT3 RA, are indicated for the prevention of chemotherapy (CT)-induced nausea and vomiting (CINV) associated with moderately (MEC) and highly emetogenic CT agents (HEC). This study explores the impact of step therapy policies requiring use of an older 5-HT3 RA before palonosetron ...

Multicultural professional psychologists routinely assert that psychotherapeutic interventions require culturally competent delivery for ethnoracial minority clients to protect the distinctive cultural orientations of these clients. Dominant disciplinary conceptualizations of cultural competence are "kind of person" models that emphasize specialized awareness, knowledge, and skills on the part ...

This research addresses the problem of what to consider as competence in research and development (R&D) and how does it change in contractual projects. Two cases are investigated, so called fault diagnosis systems and code generation methods and tools. They involve the Technical Research Centre of Finland (VTT) as a supplier and several companies as customers. Projects established by these part...

Electroporation of plasmid and chromosomal DNAs were tested in Haemophilus influenzae because of an interest in introducing DNA into mutants that are deficient in competence for transformation. The initial experiments were designed to investigate and optimize conditions for electroporation of H. influenzae. Plasmid DNA was introduced into the competence proficient strain Rd and its competence-d...

Social and health care professionals’ generic competence – survey to registered public nurses The aim of this study was assess self-evaluated in delivering optimal services social sector primary care. We assessed the relationship on job training competence, too. To explore competences as an important professional group we constructed electronic worksheet for with statements about central issues...

Learning foreign languages ​​in early childhood requires certain strategies so that learning ​​feels fun they can motivate students to learn languages. The purpose of this activity is help improve the competence teachers who are members RA/BA KKG throughout Sambi sub-district in developing teaching methods for language vocabulary childhood. One introduced TPR (Total Physical Response) based whi...

Nursing is evolving into new fields of health care including ambulance care, where a branch of specialist nursing is growing. Various views exist on the desired competence for the ambulance nurse and valid guidelines are lacking in Sweden. To increase knowledge of the field, professionals were asked to describe what competences an ambulance nurse should possess. The aim of this study was theref...

Fibroblast growth factor (Fgf) and retinoic acid (RA) signals control the formation and anteroposterior patterning of posterior hindbrain. They are also involved in development processes in other regions of the embryo. Therefore, responsiveness to Fgf and RA signals must be controlled in a context-dependent manner. Inhibiting the caudal-related genes cdx1a and cdx4 in zebrafish embryos caused e...

background: rheumatoid arthritis (ra) is a chronic inflammatory disease with many genetic factors predisposing to disease susceptibility. the aim of the present study was to investigate the impact of cd226 rs727088 and rs763361 polymorphisms and susceptibility to ra in a sample of the iranian population. methods: this case-control study was carried out on 100 patients with ra and 104 healthy su...