Gaucher's Disease (GD) is the most common lysosomal storage disease. It results from a genetic deficiency of the lysosomal enzyme ?glucocerebrosidase causing an abnormal accumulation of glucocerebrosides in macrophages. Type ? GD is the commonest, defined by the absence of neurologic involvement. Characteristic features include hepatosplenomegaly, skeletal involvement, elevated levels of serum ...

Non-azeotropic refrigerant mixtures (NARMs) are investigated for a twotemperature level heat exchange process found in a domestic refrigerator-freezer. Ideal (constant air temperature) heat exchange processes are assumed. The results allow the effects of intercooling between the evaporator refrigerant stream and the condenser outlet stream to be examined in a systematic manner. For the conditio...

In this contribution we report studies of the nature of solvation and resonance energy transfer processes in a reverse micelle (RM) upon encapsulation of a digestive enzyme, alpha-chymotrypsin (CHT). We have used one donor, Coumarin 500 (C500), and three acceptors Rhodamine 123 (R123, cationic), ethidium bromide (EtBr, cationic), and Merocyanine 540 (MC540, anionic). By selectively exciting the...

Neutrophils migrating from the blood (pH 7.35-7.45) into the surrounding tissues encounter changes in extracellular pH (pHe) conditions. Upon activation of NADPH oxidase 2 (Nox), neutrophils generate large amounts of H+ ions reducing the intracellular pH (pHi). Nevertheless, how extracellular pH regulates neutrophil extracellular trap (NET) formation (NETosis) is not clearly established. We hyp...

We present a succinct way of obtaining all possible higher dimensional generalization of Quantum Yang-Baxter Equation (QYBE). Using the scheme, we could generate the two popular three-simplex equations, namely: Zamolodchikov’s tetrahedron equation (ZTE) and Frenkel and Moore equation (FME). E-mail address: [email protected] E-mail address: [email protected] The Quantum Yang-Baxter Equation (Q...

Vle have developed a predictive corresponding states model for the thermo· physical properties of pure refrigerants and refrigerant mixtures. The bulk phase properties such as the density, enthalpy and entropy are predicted using the prin· ciple of extended corresponding states. This theoretically based model uses shape factors to insure conformality among the various components and R134a is us...

Pasteurella multocida is the causative agent of a number of diseases in animals, including fowl cholera. P. multocida strains simultaneously express two lipopolysaccharide (LPS) glycoforms (glycoforms A and B) that differ only in their inner core structure. Glycoform A contains a single 3-deoxy-d-manno-octulosonic acid (Kdo) residue that is phosphorylated by the Kdo kinase, KdkA, whereas glycof...